Z-1,3-cis-Achc-OH
Names and Identifiers of Z-1,3-cis-Achc-OH
CAS Number |
952616-39-6 |
|---|---|
EC Number |
678-375-0 |
MDL Number |
MFCD06796902 |
IUPAC Name |
(1R,3S)-3-(phenylmethoxycarbonylamino)cyclohexane-1-carboxylic acid |
InChI |
InChI=1S/C15H19NO4/c17-14(18)12-7-4-8-13(9-12)16-15(19)20-10-11-5-2-1-3-6-11/h1-3,5-6,12-13H,4,7-10H2,(H,16,19)(H,17,18)/t12-,13+/m1/s1 |
InChIKey |
LTEORMGXUMWZCU-OLZOCXBDSA-N |
Canonical SMILES |
C1CC(CC(C1)NC(=O)OCC2=CC=CC=C2)C(=O)O |
Isomeric SMILES |
C1C[C@H](C[C@H](C1)NC(=O)OCC2=CC=CC=C2)C(=O)O |
UNSPSC Code |
12352100 |
Physical and chemical properties of Z-1,3-cis-Achc-OH
Acidity coefficient |
4.61±0.10(Predicted) |
|---|---|
Boiling Point |
484.7±44.0 °C at 760 mmHg |
Density |
1.2±0.1 g/cm3 |
Exact Mass |
277.131409 |
Flash Point |
246.9±28.4 °C |
Index of Refraction |
1.565 |
LogP |
2.47 |
Melting Point |
113-114 °C |
Molecular Formula |
C15H19NO4 |
Molecular Weight |
277.316 |
PSA |
79.12000 |
Storage condition |
Sealed in dry,Room Temperature |
Vapour Pressure |
0.0±1.3 mmHg at 25°C |
Safety Information of Z-1,3-cis-Achc-OH
Applications of Z-1,3-cis-Achc-OH
Z-1,3-cis-Achc-OH has several applications across various fields:
- Pharmaceuticals: As a building block for peptide synthesis and drug design due to its ability to modify biological activity.
- Research: Used in studies involving amino acid transport mechanisms and metabolic pathways.
- Agriculture: Potential applications in developing bioactive compounds for pest control or plant growth regulation.
Interaction Studies of Z-1,3-cis-Achc-OH
Research into the interactions of Z-1,3-cis-Achc-OH with biological systems has revealed its role as an inhibitor of amino acid transporters. These studies often involve:
- Binding Affinity Assessments: Evaluating how well Z-1,3-cis-Achc-OH binds to various transporters.
- Functional Assays: Measuring the impact on amino acid uptake in cellular models.
Such studies are crucial for understanding its pharmacological potential and guiding further development.
Biological Activity of Z-1,3-cis-Achc-OH
Z-1,3-cis-Achc-OH exhibits notable biological activities, particularly as an inhibitor of certain amino acid transporters. Studies have shown that it can act as a substrate or non-transported inhibitor for the amino acid transporter SLC36A2 (PAT2), which is involved in the absorption of amino acids in the intestine. Its structural characteristics allow it to mimic natural substrates, making it a valuable compound for studying transport mechanisms and potential therapeutic applications.
Physical sample testing spectrum (NMR) of Z-1,3-cis-Achc-OH
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