(2-Methyl-2H-indazol-4-yl)boronic acid
CAS No.:
1001907-56-7
M. Wt:
175.98000
M. Fa:
C8H9BN2O2
InChI Key:
KLESGUYTRALUBQ-UHFFFAOYSA-N
Appearance:
Brown Solid
Names and Identifiers of (2-Methyl-2H-indazol-4-yl)boronic acid
CAS Number |
1001907-56-7 |
|---|---|
EC Number |
874-797-6 |
MDL Number |
MFCD09870055 |
IUPAC Name |
(2-methylindazol-4-yl)boronic acid |
InChI |
InChI=1S/C8H9BN2O2/c1-11-5-6-7(9(12)13)3-2-4-8(6)10-11/h2-5,12-13H,1H3 |
InChIKey |
KLESGUYTRALUBQ-UHFFFAOYSA-N |
Canonical SMILES |
B(C1=CC=CC2=NN(C=C12)C)(O)O |
UNSPSC Code |
12352100 |
Physical and chemical properties of (2-Methyl-2H-indazol-4-yl)boronic acid
Exact Mass |
176.07600 |
|---|---|
Molecular Formula |
C8H9BN2O2 |
Molecular Weight |
175.98000 |
PSA |
58.28000 |
Storage condition |
2-8°C |
Safety Information of (2-Methyl-2H-indazol-4-yl)boronic acid
Applications of (2-Methyl-2H-indazol-4-yl)boronic acid
(2-Methyl-2H-indazol-4-yl)boronic acid finds applications in various fields:
- Pharmaceutical Development: Its role as a proteasome inhibitor makes it a candidate for drug development, particularly in oncology.
- Organic Synthesis: It serves as an important intermediate in the synthesis of more complex organic molecules through cross-coupling reactions.
Biological Activity of (2-Methyl-2H-indazol-4-yl)boronic acid
The biological activity of (2-Methyl-2H-indazol-4-yl)boronic acid is noteworthy, particularly its role as a proteasome inhibitor. This activity suggests potential therapeutic applications in cancer treatment, where proteasome inhibitors can induce apoptosis in malignant cells. Additionally, the compound may exhibit antimicrobial properties, although further research is needed to fully elucidate its biological effects.
Physical sample testing spectrum (NMR) of (2-Methyl-2H-indazol-4-yl)boronic acid
