1-(4-Methoxyphenyl)-1H-imidazole
CAS No.:
10040-95-6
M. Wt:
174.19900
M. Fa:
C10H10N2O
InChI Key:
XNLOIFUGGCCEQX-UHFFFAOYSA-N
Appearance:
Brown Semi-Solid
Names and Identifiers of 1-(4-Methoxyphenyl)-1H-imidazole
CAS Number |
10040-95-6 |
|---|---|
EC Number |
625-159-9 |
MDL Number |
MFCD00060492 |
IUPAC Name |
1-(4-methoxyphenyl)imidazole |
InChI |
InChI=1S/C10H10N2O/c1-13-10-4-2-9(3-5-10)12-7-6-11-8-12/h2-8H,1H3 |
InChIKey |
XNLOIFUGGCCEQX-UHFFFAOYSA-N |
Canonical SMILES |
COC1=CC=C(C=C1)N2C=CN=C2 |
UNSPSC Code |
12352100 |
Physical and chemical properties of 1-(4-Methoxyphenyl)-1H-imidazole
Acidity coefficient |
5.70±0.10(Predicted) |
|---|---|
Boiling Point |
120 °C0.1 mm Hg(lit.) |
Density |
1.1g/cm3 |
Exact Mass |
174.07900 |
Flash Point |
120°C/0.1mm |
Index of Refraction |
1.57 |
LogP |
1.88090 |
Melting Point |
59-67 °C(lit.) |
Molecular Formula |
C10H10N2O |
Molecular Weight |
174.19900 |
PSA |
27.05000 |
Solubility |
>26.1 [ug/mL] (The mean of the results at pH 7.4) |
Storage condition |
2-8°C |
Vapour Pressure |
0.000741mmHg at 25°C |
Safety Information of 1-(4-Methoxyphenyl)-1H-imidazole
Applications of 1-(4-Methoxyphenyl)-1H-imidazole
This compound has several notable applications:
- Pharmaceuticals: Due to its biological activities, it is being explored as a lead compound for developing new drugs, particularly in the fields of antimicrobial and anticancer therapies.
- Chemical Research: It serves as a building block in organic synthesis for creating more complex heterocycles.
- Material Science: Its unique properties make it suitable for use in developing novel materials with specific electronic or optical characteristics.
Interaction Studies of 1-(4-Methoxyphenyl)-1H-imidazole
Interaction studies have highlighted the importance of 1-(4-Methoxyphenyl)-1H-imidazole's interactions with biomolecules:
- Protein Binding: Research indicates potential binding interactions with various proteins, which may correlate with its biological activity.
- Enzyme Inhibition: Studies suggest that it may inhibit specific enzymes involved in metabolic pathways, providing insights into its mechanism of action against pathogens or cancer cells.
Biological Activity of 1-(4-Methoxyphenyl)-1H-imidazole
Research indicates that 1-(4-Methoxyphenyl)-1H-imidazole exhibits various biological activities, including:
- Antimicrobial Properties: Studies have shown that this compound can inhibit the growth of certain bacterial strains.
- Anti-inflammatory Effects: It has been reported to reduce inflammation in experimental models, suggesting potential therapeutic applications.
- Anticancer Activity: Preliminary studies indicate that it may possess cytotoxic effects against cancer cell lines, although further research is needed to elucidate its mechanisms of action.
Physical sample testing spectrum (NMR) of 1-(4-Methoxyphenyl)-1H-imidazole
Cas:104-92-7
Cas:693-98-1
Cas:288-32-4
Cas:623-12-1
Cas:104-94-9