structure of 1-(6-amino-5-nitroindol-1-yl)ethanone

1-(6-amino-5-nitroindol-1-yl)ethanone

CAS No.: 1000343-09-8
M. Wt: 219.197
M. Fa: C10H9N3O3
InChI Key: -

Names and Identifiers of 1-(6-amino-5-nitroindol-1-yl)ethanone

CAS Number

1000343-09-8

IUPAC Name

1-(6-azanyl-5-nitro-indol-1-yl)ethanone

Canonical SMILES

CC(=O)N1C=CC2=CC(=C(C=C21)N)[N+](=O)[O-]

Physical and chemical properties of 1-(6-amino-5-nitroindol-1-yl)ethanone

Boiling Point

428.3±25.0 °C at 760 mmHg

Density

1.5±0.1 g/cm3

Exact Mass

219.064392

Flash Point

212.8±23.2 °C

Index of Refraction

1.689

LogP

1.79

Molecular Formula

C10H9N3O3

Molecular Weight

219.197

PSA

93.84000

Vapour Pressure

0.0±1.0 mmHg at 25°C

Interaction Studies of 1-(6-amino-5-nitroindol-1-yl)ethanone

Interaction studies involving 1-(6-Amino-5-nitro-1H-indol-1-yl)ethanone focus on:

  • Enzyme Inhibition: Investigating its role as an inhibitor for enzymes like xanthine oxidase, which is relevant for gout treatment.
  • Receptor Binding Studies: Understanding how this compound interacts with specific biological receptors can provide insights into its therapeutic potential.

Biological Activity of 1-(6-amino-5-nitroindol-1-yl)ethanone

Indole derivatives, including 1-(6-Amino-5-nitro-1H-indol-1-yl)ethanone, exhibit a wide range of biological activities:

  • Anticancer Activity: Indole compounds have been reported to inhibit cancer cell proliferation and induce apoptosis.
  • Antimicrobial Properties: Some indole derivatives show activity against various bacterial and fungal strains.
  • Neuroprotective Effects: Certain studies suggest potential benefits in neurodegenerative conditions due to their ability to modulate neurotransmitter systems.