structure of 5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid

5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid

CAS No.: 1000017-93-5
M. Wt: 196.59000
M. Fa: C8H5ClN2O2
InChI Key: TVUHAHMCORHJBN-UHFFFAOYSA-N

Names and Identifiers of 1000017-93-5

CAS Number

1000017-93-5

MDL Number

MFCD09836168

IUPAC Name

5-chloroimidazo[1,2-a]pyridine-2-carboxylic acid

InChI

InChI=1S/C8H5ClN2O2/c9-6-2-1-3-7-10-5(8(12)13)4-11(6)7/h1-4H,(H,12,13)

InChIKey

TVUHAHMCORHJBN-UHFFFAOYSA-N

Canonical SMILES

C1=CC2=NC(=CN2C(=C1)Cl)C(=O)O

UNSPSC Code

12352100

Physical and chemical properties of 1000017-93-5

Exact Mass

196.00400

LogP

1.68590

Melting Point

140-142℃

Molecular Formula

C8H5ClN2O2

Molecular Weight

196.59000

PSA

54.60000

Safety Information of 1000017-93-5

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000017-93-5

5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid has several potential applications:

  • Pharmaceutical Development: Its derivatives are being explored for their therapeutic potential in treating infections and cancers.
  • Chemical Probes: It can serve as a chemical probe in biological studies to understand enzyme mechanisms or cellular processes.
  • Material Science: Its unique properties may find applications in developing novel materials or coatings.

Interaction Studies of 1000017-93-5

Interaction studies involving 5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid focus on its binding affinity with various biological targets:

  • Protein-Ligand Binding: Investigations into how this compound interacts with specific proteins can provide insights into its mechanism of action against diseases.
  • Molecular Docking Studies: Computational studies have been conducted to predict how well this compound binds to target enzymes or receptors, aiding in drug design efforts.

Biological Activity of 1000017-93-5

Research indicates that 5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid exhibits significant biological activities:

  • Antimicrobial Activity: Compounds with similar structures have shown effectiveness against various bacterial strains.
  • Anticancer Potential: Studies suggest that derivatives of this compound may inhibit cancer cell proliferation, particularly in certain types of tumors such as lung and renal cancers.
  • Enzyme Inhibition: It may act as an inhibitor for specific enzymes involved in disease pathways.

Retrosynthesis analysis of 1000017-93-5

  • Route#1

    Cas:67625-36-9
    Cas:1000017-93-5