structure of 3-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid

3-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid

CAS No.: 1000017-94-6
M. Wt: 196.59000
M. Fa: C8H5ClN2O2
InChI Key: JBQOFBOMIUELMB-UHFFFAOYSA-N
Appearance: Brown Powder

Names and Identifiers of 1000017-94-6

CAS Number

1000017-94-6

MDL Number

MFCD09836169

IUPAC Name

3-chloroimidazo[1,2-a]pyridine-2-carboxylic acid

InChI

InChI=1S/C8H5ClN2O2/c9-7-6(8(12)13)10-5-3-1-2-4-11(5)7/h1-4H,(H,12,13)

InChIKey

JBQOFBOMIUELMB-UHFFFAOYSA-N

Canonical SMILES

C1=CC2=NC(=C(N2C=C1)Cl)C(=O)O

UNSPSC Code

12352100

Physical and chemical properties of 1000017-94-6

Density

1.58 g/cm3

Exact Mass

196.00400

LogP

1.68590

Melting Point

203-205℃

Molecular Formula

C8H5ClN2O2

Molecular Weight

196.59000

PSA

54.60000

Storage condition

2-8°C

Safety Information of 1000017-94-6

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000017-94-6

3-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid finds applications in several areas:

  • Pharmaceutical development: Its biological properties make it a candidate for drug development, particularly in antimicrobial and anticancer therapies.
  • Chemical research: It serves as a building block in the synthesis of more complex molecules.
  • Agricultural chemistry: Potential uses include acting as a pesticide or herbicide due to its biological activity against pathogens.

Interaction Studies of 1000017-94-6

Studies on the interactions of 3-chloroimidazo[1,2-a]pyridine-2-carboxylic acid with various biological targets have revealed important insights into its mechanism of action. For instance:

  • Enzyme inhibition studies have shown that it can inhibit specific enzymes involved in metabolic pathways related to cancer progression.
  • Binding affinity assessments indicate that it may interact with certain receptors or proteins associated with bacterial resistance mechanisms.

These interactions are crucial for understanding how this compound can be utilized therapeutically.

Biological Activity of 1000017-94-6

Research indicates that 3-chloroimidazo[1,2-a]pyridine-2-carboxylic acid possesses notable biological activities. It has been studied for its potential as an antimicrobial agent and has shown efficacy against various bacterial strains. Additionally, it has been investigated for its role in inhibiting certain enzymes that are critical for cancer cell proliferation, suggesting potential applications in oncology.

Physical sample testing spectrum (NMR) of 1000017-94-6

Physical sample testing spectrum (NMR) of 1000017-94-6