structure of 3-Chloroimidazo[1,2-a]pyridine-2-carbohydrazide

3-Chloroimidazo[1,2-a]pyridine-2-carbohydrazide

CAS No.: 1000017-99-1
M. Wt: 210.62
M. Fa: C8H7ClN4O
InChI Key: HZGMOGDKMHZGBL-UHFFFAOYSA-N

Names and Identifiers of 1000017-99-1

CAS Number

1000017-99-1

IUPAC Name

3-chloroimidazo[1,2-a]pyridine-2-carbohydrazide

InChI

InChI=1S/C8H7ClN4O/c9-7-6(8(14)12-10)11-5-3-1-2-4-13(5)7/h1-4H,10H2,(H,12,14)

InChIKey

HZGMOGDKMHZGBL-UHFFFAOYSA-N

Canonical SMILES

C1=CC2=NC(=C(N2C=C1)Cl)C(=O)NN

Physical and chemical properties of 1000017-99-1

Acidity coefficient

8.30±0.20(Predicted)

Density

1?+-.0.1 g/cm3(Predicted)

Molecular Formula

C8H7ClN4O

Molecular Weight

210.62

Applications of 1000017-99-1

3-Chloroimidazo[1,2-a]pyridine-2-carbohydrazide has a wide range of applications across various fields:

  • Chemistry: Used as a building block in synthesizing diverse heterocyclic compounds.
  • Biology: Investigated for its potential therapeutic applications, particularly in cancer treatment.
  • Industry: Employed in developing new materials and chemical processes.

Its unique structure makes it a valuable compound for further research and development.

Interaction Studies of 1000017-99-1

The mechanism of action of 3-Chloroimidazo[1,2-a]pyridine-2-carbohydrazide involves interactions with specific molecular targets. Studies have shown that it can inhibit certain enzymes linked to metabolic pathways in cancer cells, thus contributing to its cytotoxic effects. Additionally, it may interact with DNA through intercalation, further influencing its biological activity.

Biological Activity of 1000017-99-1

Research indicates that 3-Chloroimidazo[1,2-a]pyridine-2-carbohydrazide exhibits significant biological activities. It has been studied for its potential antimicrobial and anticancer properties. Specifically, it demonstrates cytotoxic activity against various cancer cell lines by inducing apoptosis and inhibiting cell proliferation. Additionally, preliminary studies suggest it may possess antifungal activity against resistant strains of Candida albicans.