structure of 1-[4-(Methylsulphonyl)naphth-1-yl]piperidine-4-carboxamide

1-[4-(Methylsulphonyl)naphth-1-yl]piperidine-4-carboxamide

CAS No.: 1000018-32-5
M. Wt: 332.417
M. Fa: C17H20N2O3S
InChI Key: BNOSSKYGNDIFCV-UHFFFAOYSA-N

Names and Identifiers of 1000018-32-5

CAS Number

1000018-32-5

IUPAC Name

1-(4-methylsulfonylnaphthalen-1-yl)piperidine-4-carboxamide

InChI

InChI=1S/C17H20N2O3S/c1-23(21,22)16-7-6-15(13-4-2-3-5-14(13)16)19-10-8-12(9-11-19)17(18)20/h2-7,12H,8-11H2,1H3,(H2,18,20)

InChIKey

BNOSSKYGNDIFCV-UHFFFAOYSA-N

Canonical SMILES

CS(=O)(=O)C1=CC=C(C2=CC=CC=C21)N3CCC(CC3)C(=O)N

Physical and chemical properties of 1000018-32-5

Boiling Point

655.0±55.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

332.119476

Flash Point

349.9±31.5 °C

Index of Refraction

1.630

LogP

0.31

Melting Point

227～230℃

Molecular Formula

C17H20N2O3S

Molecular Weight

332.417

Vapour Pressure

0.0±2.0 mmHg at 25°C

Applications of 1000018-32-5

1-[4-(Methylsulphonyl)naphth-1-yl]piperidine-4-carboxamide has potential applications in:

  • Pharmaceutical Development: Due to its structural characteristics, it is being explored as a lead compound for developing new drugs targeting cancer and neurological disorders.
  • Research Reagents: It serves as a useful reagent in proteomics and biochemical assays due to its ability to interact with various biological molecules .

Interaction Studies of 1000018-32-5

Interaction studies reveal that 1-[4-(Methylsulphonyl)naphth-1-yl]piperidine-4-carboxamide may bind to specific proteins involved in disease pathways. For instance:

  • Protein Kinases: Investigations into its binding affinity with protein kinases could elucidate its mechanism of action in cancer treatment.
  • Receptors: Studies focusing on receptor interactions may help understand its neuroprotective effects and potential applications in treating neurological disorders .

Biological Activity of 1000018-32-5

Preliminary studies suggest that 1-[4-(Methylsulphonyl)naphth-1-yl]piperidine-4-carboxamide exhibits notable biological activities. It has been investigated for:

  • Anticancer Properties: Some derivatives of piperidine compounds have shown potential in inhibiting tumor growth and inducing apoptosis in cancer cells. This compound's structural features may enhance its efficacy against specific cancer types .
  • Neuroprotective Effects: Similar compounds have been explored for their roles in neuroprotection, potentially affecting pathways involved in neurodegenerative diseases .