structure of 2-Amino-5-methylsulfonyl-4-phenyl-1,3-thiazole

2-Amino-5-methylsulfonyl-4-phenyl-1,3-thiazole

CAS No.: 1000018-51-8
M. Wt: 254.32900
M. Fa: C10H10N2O2S2
InChI Key: MENYNNGOWMJUEG-UHFFFAOYSA-N
Appearance: Solid

Names and Identifiers of 1000018-51-8

CAS Number

1000018-51-8

MDL Number

MFCD09743736

IUPAC Name

5-methylsulfonyl-4-phenyl-1,3-thiazol-2-amine

InChI

InChI=1S/C10H10N2O2S2/c1-16(13,14)9-8(12-10(11)15-9)7-5-3-2-4-6-7/h2-6H,1H3,(H2,11,12)

InChIKey

MENYNNGOWMJUEG-UHFFFAOYSA-N

Canonical SMILES

CS(=O)(=O)C1=C(N=C(S1)N)C2=CC=CC=C2

UNSPSC Code

12352100

Physical and chemical properties of 1000018-51-8

Acidity coefficient

1.03±0.10(Predicted)

Boiling Point

541.1±42.0 °C(Predicted)

Density

1.401±0.06 g/cm3(Predicted)

Exact Mass

254.01800

LogP

3.45780

Molecular Formula

C10H10N2O2S2

Molecular Weight

254.32900

PSA

109.67000

Safety Information of 1000018-51-8

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000018-51-8

The compound's unique structure and biological activity make it suitable for various applications:

  • Pharmaceutical Intermediates: It serves as an intermediate in the synthesis of pharmaceuticals, particularly those targeting infectious diseases.
  • Research Tools: Its properties make it valuable in biochemical research for studying enzyme interactions and metabolic pathways.

Interaction Studies of 1000018-51-8

Interaction studies involving 2-amino-5-methylsulfonyl-4-phenyl-1,3-thiazole focus on its reactivity with other biological molecules. These studies often assess:

  • Binding Affinity: How well the compound interacts with specific enzymes or receptors.
  • Mechanism of Action: Understanding how it exerts its biological effects at the molecular level.

Such studies are crucial for developing new therapeutic agents based on this compound.

Biological Activity of 1000018-51-8

Research indicates that derivatives of 2-amino-5-methylsulfonyl-4-phenyl-1,3-thiazole exhibit various biological activities. These include:

  • Antimicrobial Activity: Studies have shown that thiazole derivatives possess significant antibacterial properties against a range of pathogens.
  • Antileishmanial Activity: Some derivatives have been explored for their potential in treating leishmaniasis, showing promising results against trypanosomatids.
  • Antioxidant Properties: The compound has also been investigated for its antioxidant capabilities, which could have implications in preventing oxidative stress-related diseases.