structure of (1,2,3,4-Tetrahydroquinolin-7-yl)methanol

(1,2,3,4-Tetrahydroquinolin-7-yl)methanol

CAS No.: 1000045-81-7
M. Wt: 163.22
M. Fa: C10H13NO
InChI Key: CTRBFJUGIGJMCH-UHFFFAOYSA-N

Names and Identifiers of 1000045-81-7

CAS Number

1000045-81-7

EC Number

868-089-6

IUPAC Name

1,2,3,4-tetrahydroquinolin-7-ylmethanol

InChI

InChI=1S/C10H13NO/c12-7-8-3-4-9-2-1-5-11-10(9)6-8/h3-4,6,11-12H,1-2,5,7H2

InChIKey

CTRBFJUGIGJMCH-UHFFFAOYSA-N

Canonical SMILES

C1CC2=C(C=C(C=C2)CO)NC1

Physical and chemical properties of 1000045-81-7

Boiling Point

339.5±21.0 °C(Predicted)

Density

1.117±0.06 g/cm3(Predicted)

Molecular Formula

C10H13NO

Molecular Weight

163.22

Safety Information of 1000045-81-7

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000045-81-7

(1,2,3,4-Tetrahydroquinolin-7-yl)methanol has several potential applications:

  • Pharmaceuticals: Its derivatives are being explored for their roles in treating neurodegenerative diseases and cancers.
  • Biochemical Research: As a model compound, it aids in studying enzyme interactions and metabolic pathways.
  • Material Science: Its unique structure may find applications in developing novel materials with specific properties.

Interaction Studies of 1000045-81-7

Studies on (1,2,3,4-Tetrahydroquinolin-7-yl)methanol have focused on its interactions with various biological targets:

  • Enzyme Inhibition Studies: Compounds based on this structure have been evaluated for their inhibitory effects on acetylcholinesterase and other enzymes involved in neurotransmission and metabolism.
  • Binding Affinity Assessments: Research has assessed how these compounds bind to specific receptors or enzymes, providing insights into their pharmacological potential.

Biological Activity of 1000045-81-7

Research indicates that (1,2,3,4-Tetrahydroquinolin-7-yl)methanol exhibits various biological activities. Notably:

  • Acetylcholinesterase Inhibition: Compounds derived from tetrahydroquinoline structures have been studied for their potential in treating Alzheimer's disease due to their ability to inhibit acetylcholinesterase.
  • Antitumor Activity: Some derivatives have shown promising results in antitumor assays, indicating potential applications in cancer therapy.
  • CYP Enzyme Interaction: This compound interacts with cytochrome P450 enzymes, particularly CYP1A2, suggesting implications for drug metabolism and pharmacokinetics.