structure of 6-Bromo-2-cyclohexylquinazolin-4(3H)-one

6-Bromo-2-cyclohexylquinazolin-4(3H)-one

CAS No.: 1000339-29-6
M. Wt: 307.18600
M. Fa: C14H15BrN2O
InChI Key: -

Names and Identifiers of 1000339-29-6

CAS Number

1000339-29-6

IUPAC Name

6-bromanyl-2-cyclohexyl-3H-quinazolin-4-one

Canonical SMILES

C1CCC(CC1)C2=NC3=C(C=C(C=C3)Br)C(=O)N2

Physical and chemical properties of 1000339-29-6

Exact Mass

306.03700

LogP

3.73330

Molecular Formula

C14H15BrN2O

Molecular Weight

307.18600

PSA

45.75000

Storage condition

2-8°C

Applications of 1000339-29-6

6-Bromo-2-cyclohexylquinazolin-4(3H)-one has potential applications in:

  • Pharmaceutical Development: Due to its biological activities, it could serve as a lead compound for developing new antimicrobial or anticancer drugs.
  • Chemical Research: It may be used as an intermediate in the synthesis of more complex heterocyclic compounds.
  • Material Science: Investigations into its properties may reveal applications in organic electronics or photonic devices.

Interaction Studies of 1000339-29-6

Interaction studies involving 6-bromo-2-cyclohexylquinazolin-4(3H)-one focus on its binding affinity to various biological targets, including enzymes and receptors. These studies typically employ techniques such as:

  • Molecular Docking: To predict how the compound interacts with specific proteins involved in disease pathways.
  • In Vitro Assays: To evaluate its effectiveness against cultured cells or microbial strains.

Understanding these interactions is crucial for elucidating the compound's mechanism of action and potential therapeutic uses.

Biological Activity of 1000339-29-6

Quinazolinone derivatives, including 6-bromo-2-cyclohexylquinazolin-4(3H)-one, have shown promising biological activities. They are known for:

  • Antimicrobial Activity: Studies indicate that quinazolinones exhibit antibacterial properties against various pathogens .
  • Anticancer Properties: Some derivatives have been investigated for their ability to inhibit cancer cell proliferation and induce apoptosis .
  • Anti-inflammatory Effects: Certain compounds in this class have demonstrated potential in reducing inflammation in experimental models.

The specific biological activity of 6-bromo-2-cyclohexylquinazolin-4(3H)-one would require empirical testing to establish its efficacy and mechanism of action.