structure of 2-[4-(Trifluoromethyl)piperidino]-1,3-thiazole-5-carbaldehyde

2-[4-(Trifluoromethyl)piperidino]-1,3-thiazole-5-carbaldehyde

CAS No.: 1000339-88-7
M. Wt: 264.27
M. Fa: C10H11F3N2OS
InChI Key: DGADTZIGHLQBTO-UHFFFAOYSA-N

Names and Identifiers of 1000339-88-7

CAS Number

1000339-88-7

IUPAC Name

2-[4-(trifluoromethyl)piperidin-1-yl]-1,3-thiazole-5-carbaldehyde

InChI

InChI=1S/C10H11F3N2OS/c11-10(12,13)7-1-3-15(4-2-7)9-14-5-8(6-16)17-9/h5-7H,1-4H2

InChIKey

DGADTZIGHLQBTO-UHFFFAOYSA-N

Canonical SMILES

C1CN(CCC1C(F)(F)F)C2=NC=C(S2)C=O

Physical and chemical properties of 1000339-88-7

Melting Point

42～45℃

Molecular Formula

C10H11F3N2OS

Molecular Weight

264.27

Safety Information of 1000339-88-7

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000339-88-7

The primary applications of 2-[4-(Trifluoromethyl)piperidino]-1,3-thiazole-5-carbaldehyde are in research settings focused on:

  • Medicinal Chemistry: As a scaffold for developing new drugs targeting various diseases.
  • Chemical Biology: Studying its interactions with biological molecules to understand mechanisms of action.
  • Synthetic Chemistry: Serving as an intermediate in the synthesis of other biologically active compounds .

Interaction Studies of 1000339-88-7

Interaction studies involving 2-[4-(Trifluoromethyl)piperidino]-1,3-thiazole-5-carbaldehyde often focus on its binding affinity to various biological targets. Preliminary studies suggest that it may interact with enzymes involved in metabolic pathways or with receptors modulating physiological responses. These interactions are critical for understanding its potential therapeutic effects and side effects .

Biological Activity of 1000339-88-7

Research indicates that 2-[4-(Trifluoromethyl)piperidino]-1,3-thiazole-5-carbaldehyde exhibits various biological activities. It has been studied for its potential as an antimicrobial agent and as a precursor for compounds with anti-inflammatory properties. The trifluoromethyl group is known to enhance biological activity by increasing membrane permeability and altering pharmacokinetic profiles .