![structure of 3-bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine](https://molwiki.oss-cn-hongkong.aliyuncs.com/structure/20/1000340-20-4.svg)
3-bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine
Names and Identifiers of 1000340-20-4
CAS Number |
1000340-20-4 |
|---|---|
IUPAC Name |
3-bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine |
InChI |
InChI=1S/C8H6BrN3O2/c1-4-7(12(13)14)2-5-6(9)3-10-8(5)11-4/h2-3H,1H3,(H,10,11) |
InChIKey |
OAVGDDMDWNKGOE-UHFFFAOYSA-N |
Canonical SMILES |
CC1=C(C=C2C(=CNC2=N1)Br)[N+](=O)[O-] |
Physical and chemical properties of 1000340-20-4
Density |
1.8±0.1 g/cm3 |
|---|---|
Exact Mass |
254.964325 |
Index of Refraction |
1.731 |
LogP |
3.81 |
Molecular Formula |
C8H6BrN3O2 |
Molecular Weight |
256.056 |
PSA |
74.50000 |
Interaction Studies of 1000340-20-4
Studies on interaction mechanisms suggest that 3-bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine may interact with fibroblast growth factor receptors (FGFRs), which play crucial roles in cell proliferation and differentiation. This interaction could lead to significant implications in cancer therapeutics, particularly in inhibiting tumor growth .
Biological Activity of 1000340-20-4
The biological activity of 3-bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine is notable for its potential interactions with biological targets. The nitro group may undergo bioreduction to form reactive intermediates that affect cellular components. The compound has shown promise in modulating biological pathways through interactions with specific enzymes or receptors, which may be relevant for therapeutic applications .