structure of 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic  acid,  6-methyl-5-nitro-

1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 6-methyl-5-nitro-

CAS No.: 1000340-25-9
M. Wt: 221.170
M. Fa: C9H7N3O4
InChI Key: -

Names and Identifiers of 1000340-25-9

CAS Number

1000340-25-9

IUPAC Name

6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Canonical SMILES

CC1=C(C=C2C(=CNC2=N1)C(=O)O)[N+](=O)[O-]

Physical and chemical properties of 1000340-25-9

Density

1.6±0.1 g/cm3

Exact Mass

221.043655

Index of Refraction

1.743

LogP

2.67

Molecular Formula

C9H7N3O4

Molecular Weight

221.170

PSA

111.80000

Applications of 1000340-25-9

6-Methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid has potential applications in:

  • Medicinal Chemistry: As a precursor for synthesizing novel pharmacological agents targeting cancer and other diseases.
  • Biochemical Research: As a tool for studying specific biological pathways and interactions due to its unique structural properties.

Its ability to undergo diverse chemical modifications makes it a versatile compound in drug development processes.

Interaction Studies of 1000340-25-9

Studies exploring the interactions of 6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid with biological targets are crucial for understanding its mechanism of action. Research indicates that modifications to its structure can enhance binding affinity to specific receptors or enzymes involved in disease processes. For example, derivatives have been evaluated for their inhibitory effects on fibroblast growth factor receptors, demonstrating significant interactions that could lead to therapeutic applications in oncology.

Biological Activity of 1000340-25-9

The biological activity of 6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid has been investigated due to its potential as an inhibitor of various biological pathways. Its structural features suggest that it may interact with specific proteins involved in cellular signaling pathways, particularly those related to cancer progression. For instance, derivatives of pyrrolo[2,3-b]pyridine have shown promise as fibroblast growth factor receptor inhibitors, which are relevant in the treatment of tumors associated with aberrant signaling pathways.