structure of 6-Bromo-4-chloro-1H-pyrrolo[2,3-B]pyridine

6-Bromo-4-chloro-1H-pyrrolo[2,3-B]pyridine

CAS No.: 1000340-64-6
M. Wt: 231.477
M. Fa: C7H4BrClN2
InChI Key: OVLYMSBXUYTCSP-UHFFFAOYSA-N
Appearance: light purple solid

Names and Identifiers of 1000340-64-6

CAS Number

1000340-64-6

MDL Number

MFCD09880150

IUPAC Name

6-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine

InChI

InChI=1S/C7H4BrClN2/c8-6-3-5(9)4-1-2-10-7(4)11-6/h1-3H,(H,10,11)

InChIKey

OVLYMSBXUYTCSP-UHFFFAOYSA-N

Canonical SMILES

C1=CNC2=C1C(=CC(=N2)Br)Cl

UNSPSC Code

12352100

Physical and chemical properties of 1000340-64-6

Density

1.9±0.1 g/cm3

Exact Mass

229.924637

Index of Refraction

1.730

LogP

3.30

Molecular Formula

C7H4BrClN2

Molecular Weight

231.477

PSA

28.68000

Safety Information of 1000340-64-6

Pictograms

Signal Word

 Warning

Safety Data Sheet
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Applications of 1000340-64-6

The unique properties of 6-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine make it suitable for various applications:

  • Medicinal Chemistry: It is investigated for its potential therapeutic effects against cancer and infectious diseases due to its enzyme-inhibiting properties.
  • Material Science: The compound serves as a building block in the synthesis of novel materials with specific electronic or optical properties.
  • Chemical Research: Its role as an intermediate in organic synthesis facilitates the development of complex molecules in pharmaceutical research.

Interaction Studies of 1000340-64-6

Studies on the interactions of 6-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine with biomolecules have shown that it can bind to specific enzyme active sites. This binding often leads to inhibition or modulation of enzyme activity. Furthermore, its interactions with receptors may influence various signaling pathways within cells, highlighting its potential as a therapeutic agent. Ongoing research aims to elucidate these mechanisms further to optimize its use in drug development.

Biological Activity of 1000340-64-6

Research indicates that 6-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine exhibits significant biological activities. It has been studied for its potential as an inhibitor of various enzymes, particularly kinases involved in cellular signaling pathways. This inhibition can affect processes such as cell proliferation and apoptosis, making it a candidate for further investigation in cancer research and drug development. Additionally, its interactions with other biomolecules suggest potential roles in modulating receptor activity and influencing biochemical pathways.