structure of 6-Bromo-1H-pyrrolo[2,3-b]pyridin-4-amine

6-Bromo-1H-pyrrolo[2,3-b]pyridin-4-amine

CAS No.: 1000340-72-6
M. Wt: 212.047
M. Fa: C7H6BrN3
InChI Key: WIPJXNLJOYTTKC-UHFFFAOYSA-N
Appearance: white solid

Names and Identifiers of 1000340-72-6

CAS Number

1000340-72-6

MDL Number

MFCD09880154

IUPAC Name

6-bromo-1H-pyrrolo[2,3-b]pyridin-4-amine

InChI

InChI=1S/C7H6BrN3/c8-6-3-5(9)4-1-2-10-7(4)11-6/h1-3H,(H3,9,10,11)

InChIKey

WIPJXNLJOYTTKC-UHFFFAOYSA-N

Canonical SMILES

C1=CNC2=C1C(=CC(=N2)Br)N

UNSPSC Code

12352100

Physical and chemical properties of 1000340-72-6

Boiling Point

442.8±40.0 °C at 760 mmHg

Density

1.9±0.1 g/cm3

Exact Mass

210.974503

Flash Point

221.6±27.3 °C

Index of Refraction

1.800

LogP

2.60

Molecular Formula

C7H6BrN3

Molecular Weight

212.047

PSA

54.70000

Storage condition

2-8°C(protect from light)

Vapour Pressure

0.0±1.1 mmHg at 25°C

Safety Information of 1000340-72-6

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000340-72-6

6-Bromo-1H-pyrrolo[2,3-b]pyridin-4-amine finds applications in several areas:

  • Pharmaceutical Research: Its ability to inhibit specific enzymes makes it a candidate for drug development targeting various diseases.
  • Biochemical Studies: The compound is utilized in studying enzyme mechanisms and cellular signaling pathways due to its interaction with kinases and other proteins .

Interaction Studies of 1000340-72-6

Research indicates that 6-Bromo-1H-pyrrolo[2,3-b]pyridin-4-amine interacts with multiple biological targets. Its selectivity for certain kinases can be exploited for therapeutic purposes. Interaction studies have shown its potential in modulating pathways involved in cancer and inflammatory responses .

Biological Activity of 1000340-72-6

This compound exhibits significant biological activity, primarily through its interactions with specific enzymes. It has been shown to inhibit various kinases, which are critical for regulating cellular processes. The binding of 6-Bromo-1H-pyrrolo[2,3-b]pyridin-4-amine to the active sites of these enzymes can lead to modulation or inhibition of their activity. Furthermore, it may interact with other biomolecules, including receptors and signaling proteins, thereby influencing cellular signaling pathways .