structure of 4-methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

4-methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

CAS No.: 1000341-31-0
M. Wt: 176.172
M. Fa: C9H8N2O2
InChI Key: FYWALQVURBDJKB-UHFFFAOYSA-N
Appearance: Light Yellow to Yellow Solid

Names and Identifiers of 1000341-31-0

CAS Number

1000341-31-0

IUPAC Name

4-methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

InChI

InChI=1S/C9H8N2O2/c1-13-9-8-6(5-12)4-11-7(8)2-3-10-9/h2-5,11H,1H3

InChIKey

FYWALQVURBDJKB-UHFFFAOYSA-N

Canonical SMILES

COC1=NC=CC2=C1C(=CN2)C=O

Physical and chemical properties of 1000341-31-0

Boiling Point

383.2±37.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

176.058578

Flash Point

185.6±26.5 °C

Index of Refraction

1.691

LogP

0.79

Molecular Formula

C9H8N2O2

Molecular Weight

176.172

PSA

54.98000

Storage condition

under inert gas (nitrogen or Argon) at 2-8°C

Vapour Pressure

0.0±0.9 mmHg at 25°C

Applications of 1000341-31-0

4-Methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde has several applications across different fields:

  • Chemistry: It serves as a building block for synthesizing more complex heterocyclic compounds.
  • Biology: It acts as a precursor for developing biologically active molecules, including potential drug candidates.
  • Medicine: Its role as an enzyme inhibitor positions it as a candidate for drug development targeting specific diseases.
  • Industry: The compound is also explored for developing materials with unique electronic or optical properties.

Interaction Studies of 1000341-31-0

Studies focusing on the interactions of 4-methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde with biological targets have revealed its capability to inhibit FGFR activity effectively. This interaction leads to downstream effects on cellular pathways involved in tumor growth and metastasis. Understanding these interactions is vital for elucidating the compound's mechanism of action and potential therapeutic applications in oncology.

Biological Activity of 1000341-31-0

Research indicates that 4-methoxy-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde exhibits significant biological activity, particularly as an inhibitor of fibroblast growth factor receptors (FGFRs). FGFRs play crucial roles in various cellular processes, including cell proliferation and angiogenesis. The inhibition of these receptors by this compound suggests potential applications in cancer therapy, where modulation of growth factor signaling pathways can be beneficial. Additionally, preliminary studies have shown that this compound may induce apoptosis in cancer cells, further supporting its therapeutic potential.