structure of 7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

CAS No.: 1000342-10-8
M. Wt: 259.487
M. Fa: C8H4BrClN2O
InChI Key: DYVSZDIBJBRTAF-UHFFFAOYSA-N

Names and Identifiers of 1000342-10-8

CAS Number

1000342-10-8

IUPAC Name

7-bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

InChI

InChI=1S/C8H4BrClN2O/c9-5-2-12-8(10)6-4(3-13)1-11-7(5)6/h1-3,11H

InChIKey

DYVSZDIBJBRTAF-UHFFFAOYSA-N

Canonical SMILES

C1=C(C2=C(N1)C(=CN=C2Cl)Br)C=O

Physical and chemical properties of 1000342-10-8

Boiling Point

444.0±40.0 °C at 760 mmHg

Density

1.9±0.1 g/cm3

Exact Mass

257.919556

Flash Point

222.3±27.3 °C

Index of Refraction

1.768

LogP

1.83

Molecular Formula

C8H4BrClN2O

Molecular Weight

259.487

PSA

45.75000

Vapour Pressure

0.0±1.1 mmHg at 25°C

Applications of 1000342-10-8

7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde has several applications across different fields:

  • Medicinal Chemistry: It serves as a building block in the synthesis of more complex molecules with potential therapeutic effects.
  • Biological Research: Its role as a kinase inhibitor makes it valuable in studies related to cancer and other diseases.
  • Material Science: The compound may also find applications in developing new materials due to its unique chemical properties.

Interaction Studies of 1000342-10-8

Studies on the interaction of 7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde with specific molecular targets have shown that it effectively inhibits certain kinases involved in critical signaling pathways. This inhibition can lead to reduced cell proliferation and increased apoptosis in cancer cells. Understanding these interactions further elucidates its potential therapeutic mechanisms and guides future research into its applications in drug development.

Biological Activity of 1000342-10-8

Research indicates that 7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde exhibits significant biological activity, particularly as a kinase inhibitor. This property is crucial for studying cell signaling pathways and has implications in cancer research. By inhibiting specific kinases, this compound can disrupt cellular processes such as proliferation and survival, making it a candidate for therapeutic development against various diseases.