structure of 6-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine

6-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine

CAS No.: 1000342-81-3
M. Wt: 227.058
M. Fa: C8H7BrN2O
InChI Key: YEXAAABKHINEAN-UHFFFAOYSA-N

Names and Identifiers of 1000342-81-3

CAS Number

1000342-81-3

MDL Number

MFCD09749967

IUPAC Name

6-bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine

InChI

InChI=1S/C8H7BrN2O/c1-12-8-5-2-3-10-6(5)4-7(9)11-8/h2-4,10H,1H3

InChIKey

YEXAAABKHINEAN-UHFFFAOYSA-N

Canonical SMILES

COC1=C2C=CNC2=CC(=N1)Br

UNSPSC Code

12352100

Physical and chemical properties of 1000342-81-3

Boiling Point

357.1±37.0 °C at 760 mmHg

Density

1.7±0.1 g/cm3

Exact Mass

225.974167

Flash Point

169.8±26.5 °C

H Bond Acceptors

2

H Bond Donors

1

Index of Refraction

1.678

LogP

2.17

Molecular Formula

C8H7BrN2O

Molecular Weight

227.058

PSA

37.91000

Vapour Pressure

0.0±0.8 mmHg at 25°C

Safety Information of 1000342-81-3

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000342-81-3

6-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine has several applications:

  • Pharmaceutical Development: As a lead compound for developing new drugs targeting cancer and metabolic diseases.
  • Research Tool: Used in biochemical research to study enzyme inhibition and other biological pathways.
  • Material Science: Potential applications in developing novel materials due to its unique electronic properties.

Interaction Studies of 1000342-81-3

Interaction studies involving 6-bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine often focus on:

  • Protein Binding Assays: Investigating how the compound interacts with various proteins implicated in disease pathways.
  • Cell Line Studies: Evaluating cytotoxicity and efficacy against cancer cell lines to understand its therapeutic potential.
  • Mechanistic Studies: Understanding the mechanism of action through which it exerts its biological effects, particularly in enzyme inhibition.

Biological Activity of 1000342-81-3

Research indicates that compounds related to 1H-pyrrolo[3,2-c]pyridine derivatives exhibit significant biological activities, including:

  • Anticancer Activity: Some derivatives have shown promise as inhibitors of cancer cell proliferation by targeting specific pathways involved in tumor growth.
  • Enzyme Inhibition: Certain studies have highlighted their potential as inhibitors of acetyl-CoA carboxylase, an enzyme involved in lipid metabolism, which could be beneficial in treating metabolic disorders .
  • Antimicrobial Properties: Similar compounds have been investigated for their antimicrobial effects, indicating a broad spectrum of potential therapeutic uses.