structure of 5-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine

5-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine

CAS No.: 1000343-82-7
M. Wt: 336.955
M. Fa: C8H6BrIN2
InChI Key: QGLDJMOMZDVFFR-UHFFFAOYSA-N
Appearance: Yellow Solid

Names and Identifiers of 1000343-82-7

CAS Number

1000343-82-7

MDL Number

MFCD09880096

IUPAC Name

5-bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine

InChI

InChI=1S/C8H6BrIN2/c1-4-6(9)2-5-7(10)3-11-8(5)12-4/h2-3H,1H3,(H,11,12)

InChIKey

QGLDJMOMZDVFFR-UHFFFAOYSA-N

Canonical SMILES

CC1=C(C=C2C(=CNC2=N1)I)Br

UNSPSC Code

12352100

Physical and chemical properties of 1000343-82-7

Density

2.3±0.1 g/cm3

Exact Mass

335.875885

Index of Refraction

1.768

LogP

4.32

Molecular Formula

C8H6BrIN2

Molecular Weight

336.955

PSA

28.68000

Storage condition

2-8°C(protect from light)

Safety Information of 1000343-82-7

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1000343-82-7

The compound has several applications across various fields:

  • Medicinal Chemistry: Due to its biological activity against cancer cell proliferation, it is being investigated as a potential lead compound for drug development targeting FGFR-related pathways.
  • Organic Synthesis: Its unique structure allows it to serve as an intermediate in the synthesis of more complex organic molecules.

The versatility of this compound makes it valuable in both academic research and industrial applications.

Interaction Studies of 1000343-82-7

Interaction studies involving 5-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine focus on its binding affinity to specific proteins or enzymes implicated in disease pathways. Research has shown that this compound can effectively interact with targets involved in cancer progression, providing insights into its mechanism of action and potential therapeutic benefits. Understanding these interactions is crucial for developing new therapeutics based on this compound class.

Biological Activity of 1000343-82-7

Research indicates that 5-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine exhibits significant biological activity, particularly in cancer research. It has been shown to inhibit the proliferation of cancer cells by modulating key signaling pathways, including the fibroblast growth factor receptor (FGFR) pathway. This inhibition may lead to reduced cell migration and invasion, indicating its potential as a therapeutic agent against various cancers.

Physical sample testing spectrum (NMR) of 1000343-82-7

Physical sample testing spectrum (NMR) of 1000343-82-7