structure of 4-Chloro-6,7-dimethoxy-2-methylquinoline

4-Chloro-6,7-dimethoxy-2-methylquinoline

CAS No.: 100122-02-9
M. Wt: 237.68200
M. Fa: C12H12ClNO2
InChI Key: RBFMLSFDCICSHW-UHFFFAOYSA-N
Appearance: Off white solid

Names and Identifiers of 100122-02-9

CAS Number

100122-02-9

MDL Number

MFCD11868302

IUPAC Name

4-chloro-6,7-dimethoxy-2-methylquinoline

InChI

InChI=1S/C12H12ClNO2/c1-7-4-9(13)8-5-11(15-2)12(16-3)6-10(8)14-7/h4-6H,1-3H3

InChIKey

RBFMLSFDCICSHW-UHFFFAOYSA-N

Canonical SMILES

CC1=CC(=C2C=C(C(=CC2=N1)OC)OC)Cl

UNSPSC Code

12352100

Physical and chemical properties of 100122-02-9

Exact Mass

237.05600

H Bond Acceptors

3

H Bond Donors

0

LogP

3.21380

Molecular Formula

C12H12ClNO2

Molecular Weight

237.68200

PSA

31.35000

Storage condition

under inert gas (nitrogen or Argon) at 2-8°C

Safety Information of 100122-02-9

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 100122-02-9

The applications of 4-chloro-6,7-dimethoxy-2-methylquinoline span various fields:

  • Pharmaceutical Development: Due to its biological activity, it is being explored for use in developing new anticancer and antimicrobial drugs.
  • Chemical Research: It serves as a versatile building block for synthesizing other quinoline derivatives and studying their properties.

Interaction Studies of 100122-02-9

Interaction studies have revealed that 4-chloro-6,7-dimethoxy-2-methylquinoline interacts with various biological targets:

  • Enzyme Inhibition: It has been shown to inhibit certain kinases associated with cancer progression.
  • Binding Affinity: The compound demonstrates significant binding affinity to target proteins involved in metabolic pathways relevant to disease states.

Biological Activity of 100122-02-9

Research indicates that 4-chloro-6,7-dimethoxy-2-methylquinoline possesses significant biological activities, including:

  • Anticancer Properties: It has shown potential as an inhibitor of certain cancer cell lines, particularly through its interaction with specific enzymes involved in tumor growth.
  • Antimicrobial Activity: The compound exhibits antimicrobial properties against various bacterial strains, making it a candidate for further pharmaceutical development.

Physical sample testing spectrum (NMR) of 100122-02-9

Physical sample testing spectrum (NMR) of 100122-02-9