structure of (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide

(R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide

CAS No.: 1001908-89-9
M. Wt: 468.57
M. Fa: C27H24N4O2S
InChI Key: MUFSINOSQBMSLE-JOCHJYFZSA-N
Appearance: Pale-yellow Solid

Names and Identifiers of 1001908-89-9

CAS Number

1001908-89-9

IUPAC Name

N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide

InChI

InChI=1S/C27H24N4O2S/c32-22-11-12-30(15-22)14-21-17-34-27-29-25(16-31(21)27)23-7-3-4-8-24(23)28-26(33)20-10-9-18-5-1-2-6-19(18)13-20/h1-10,13,16-17,22,32H,11-12,14-15H2,(H,28,33)/t22-/m1/s1

InChIKey

MUFSINOSQBMSLE-JOCHJYFZSA-N

Canonical SMILES

C1CN(CC1O)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=CC6=CC=CC=C6C=C5

Isomeric SMILES

C1CN(C[C@@H]1O)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=CC6=CC=CC=C6C=C5

UNII

6FKU9G9CX6

Physical and chemical properties of 1001908-89-9

Exact Mass

468.16200

LogP

5.04580

Molecular Formula

C27H24N4O2S

Molecular Weight

468.57

PSA

98.11000

Storage condition

-20℃

Applications of 1001908-89-9

The potential applications of (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide are vast:

  • Pharmaceutical Development: Given its biological activity, it may serve as a lead compound for new drug formulations targeting infections or cancer.
  • Research Tool: It could be used in biochemical assays to study specific pathways or interactions within cellular systems.

Interaction Studies of 1001908-89-9

Interaction studies are crucial for understanding how (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide interacts with biological targets:

  • Binding Affinity Studies: Assessing how well the compound binds to specific receptors or enzymes can provide insights into its mechanism of action.
  • Cellular Assays: Evaluating the compound's effects on cell viability and proliferation can help determine its therapeutic potential.

Biological Activity of 1001908-89-9

Preliminary studies indicate that (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide exhibits significant biological activity. Its structure suggests potential interactions with various biological targets, including:

  • Antimicrobial Activity: Compounds with similar structural features have shown effectiveness against various bacterial strains.
  • Anticancer Properties: The imidazo-thiazole moiety is often associated with anticancer activity, making this compound a candidate for further investigation in cancer therapy.

Research has highlighted the importance of such compounds in drug discovery due to their diverse biological profiles .

Physical sample testing spectrum (NMR) of 1001908-89-9

Physical sample testing spectrum (NMR) of 1001908-89-9