structure of 1H-Pyrrolo[3,2-c]pyridin-3-amine

1H-Pyrrolo[3,2-c]pyridin-3-amine

CAS No.: 1000342-62-0
M. Wt: 133.151
M. Fa: C7H7N3
InChI Key: PVXULIOPYOMGME-UHFFFAOYSA-N

Names and Identifiers of 1H-Pyrrolo[3,2-c]pyridin-3-amine

CAS Number

1000342-62-0

MDL Number

MFCD09026946

IUPAC Name

1H-pyrrolo[3,2-c]pyridin-3-amine

InChI

InChI=1S/C7H7N3/c8-6-4-10-7-1-2-9-3-5(6)7/h1-4,10H,8H2

InChIKey

PVXULIOPYOMGME-UHFFFAOYSA-N

Canonical SMILES

C1=CN=CC2=C1NC=C2N

UNSPSC Code

12352100

Physical and chemical properties of 1H-Pyrrolo[3,2-c]pyridin-3-amine

Boiling Point

404.0±25.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

133.063995

Flash Point

227.1±10.4 °C

H Bond Acceptors

2

H Bond Donors

2

Index of Refraction

1.780

LogP

-0.63

Molecular Formula

C7H7N3

Molecular Weight

133.151

PSA

54.70000

Storage condition

2-8°C(protect from light)

Vapour Pressure

0.0±0.9 mmHg at 25°C

Safety Information of 1H-Pyrrolo[3,2-c]pyridin-3-amine

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 1H-Pyrrolo[3,2-c]pyridin-3-amine

1H-Pyrrolo[3,2-c]pyridin-3-amine finds utility in various fields:

  • Medicinal Chemistry: It serves as a scaffold for developing new therapeutic agents, particularly those targeting cancer.
  • Chemical Biology: The compound is used in studies to explore biological pathways and mechanisms due to its ability to interact with specific molecular targets.
  • Material Science: Its derivatives may be applied in the development of advanced materials owing to their unique electronic properties.

Interaction Studies of 1H-Pyrrolo[3,2-c]pyridin-3-amine

Research into the interaction of 1H-Pyrrolo[3,2-c]pyridin-3-amine with biological targets has revealed its potential as a kinase inhibitor. Studies have demonstrated that certain derivatives can effectively disrupt key signaling pathways involved in tumor growth and metastasis. For instance, compounds derived from this structure have been shown to inhibit tubulin polymerization, impacting cell cycle dynamics and apoptosis in cancer cells.

Biological Activity of 1H-Pyrrolo[3,2-c]pyridin-3-amine

1H-Pyrrolo[3,2-c]pyridin-3-amine has garnered attention due to its biological activities, particularly as an inhibitor of various enzymes and receptors. Studies have indicated that derivatives of this compound may exhibit:

  • Antitumor Activity: Some derivatives have shown potent activity against cancer cell lines, indicating potential as anticancer agents.
  • Inhibition of Kinases: The compound has been investigated for its ability to inhibit receptor tyrosine kinases, which are critical in many signaling pathways related to cancer progression.