2-(Bromomethyl)-6-fluoropyridine
Names and Identifiers of 2-(Bromomethyl)-6-fluoropyridine
CAS Number |
100202-78-6 |
|---|---|
EC Number |
815-302-5 |
MDL Number |
MFCD09953532 |
IUPAC Name |
2-(bromomethyl)-6-fluoropyridine |
InChI |
InChI=1S/C6H5BrFN/c7-4-5-2-1-3-6(8)9-5/h1-3H,4H2 |
InChIKey |
ADYKBYXVMBDQQX-UHFFFAOYSA-N |
Canonical SMILES |
C1=CC(=NC(=C1)F)CBr |
UNSPSC Code |
12352100 |
Physical and chemical properties of 2-(Bromomethyl)-6-fluoropyridine
Acidity coefficient |
-2.22±0.12(Predicted) |
|---|---|
Boiling Point |
208.8±25.0 °C at 760 mmHg |
Density |
1.6±0.1 g/cm3 |
Exact Mass |
188.958939 |
Flash Point |
80.1±23.2 °C |
Index of Refraction |
1.549 |
LogP |
1.54 |
Molecular Formula |
C6H5BrFN |
Molecular Weight |
190.013 |
PSA |
12.89000 |
Storage condition |
2-8°C |
Vapour Pressure |
0.3±0.4 mmHg at 25°C |
Safety Information of 2-(Bromomethyl)-6-fluoropyridine
Applications of 2-(Bromomethyl)-6-fluoropyridine
2-(Bromomethyl)-6-fluoropyridine serves as a valuable building block in organic synthesis. Its applications include:
- Synthesis of Pharmaceuticals: It is used to create various pharmaceutical intermediates.
- Development of Agrochemicals: The compound can be utilized in synthesizing agrochemical products.
- Research
Interaction Studies of 2-(Bromomethyl)-6-fluoropyridine
Interaction studies involving 2-(Bromomethyl)-6-fluoropyridine focus on its reactivity with nucleophiles and electrophiles. These studies help elucidate its potential as a precursor for biologically active compounds. Additionally, investigations into its interactions with enzymes or receptors could provide insights into its pharmacological properties and therapeutic potential.
Biological Activity of 2-(Bromomethyl)-6-fluoropyridine
While specific biological activities of 2-(Bromomethyl)-6-fluoropyridine are not extensively documented, compounds with similar structures often exhibit significant pharmacological properties. Pyridine derivatives are known for their roles in medicinal chemistry, including antibacterial, antifungal, and antitumor activities. The presence of halogen substituents like bromine and fluorine can enhance biological activity through increased lipophilicity and improved binding interactions with biological targets.
Physical sample testing spectrum (NMR) of 2-(Bromomethyl)-6-fluoropyridine
Cas:407-22-7
