2-Fluoro-5-iodo-4-methoxybenzoic acid
Names and Identifiers of 2-Fluoro-5-iodo-4-methoxybenzoic acid
CAS Number |
1000162-78-6 |
|---|---|
IUPAC Name |
2-fluoro-5-iodo-4-methoxybenzoic acid |
InChI |
InChI=1S/C8H6FIO3/c1-13-7-3-5(9)4(8(11)12)2-6(7)10/h2-3H,1H3,(H,11,12) |
InChIKey |
MDNCZSISNHLNOY-UHFFFAOYSA-N |
Canonical SMILES |
COC1=C(C=C(C(=C1)F)C(=O)O)I |
Physical and chemical properties of 2-Fluoro-5-iodo-4-methoxybenzoic acid
Exact Mass |
295.93500 |
|---|---|
LogP |
2.13710 |
Molecular Formula |
C8H6FIO3 |
Molecular Weight |
296.03400 |
PSA |
46.53000 |
Applications of 2-Fluoro-5-iodo-4-methoxybenzoic acid
2-Fluoro-5-iodo-4-methoxybenzoic acid finds utility in various fields:
- Pharmaceuticals: It serves as an intermediate in the synthesis of bioactive compounds, particularly in drug discovery and development.
- Organic Synthesis: The compound acts as a building block in creating complex organic molecules through various coupling reactions.
- Material Science: Its unique properties make it suitable for developing new materials with specific functionalities, such as sensors or catalysts.
Interaction Studies of 2-Fluoro-5-iodo-4-methoxybenzoic acid
Studies on similar halogenated compounds have revealed interesting interaction profiles with biological targets. For example, 2-Fluoro-5-iodophenylboronic acid has shown promising antibacterial activity against various pathogens. Interaction studies typically focus on:
- Binding Affinity: Assessing how well the compound binds to target proteins or enzymes.
- Mechanism of Action: Investigating how the compound exerts its biological effects at the molecular level.
These studies are crucial for understanding the potential therapeutic applications of 2-Fluoro-5-iodo-4-methoxybenzoic acid.
Biological Activity of 2-Fluoro-5-iodo-4-methoxybenzoic acid
Research indicates that halogenated compounds, including 2-Fluoro-5-iodo-4-methoxybenzoic acid, often exhibit significant biological activities. For instance, similar compounds have demonstrated antibacterial and antifungal properties, potentially due to their ability to disrupt microbial cell membranes or inhibit essential enzymes. Studies suggest that the presence of halogens can enhance the lipophilicity of the compounds, facilitating better interaction with biological membranes.