structure of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

CAS No.: 1000341-07-0
M. Wt: 305.954
M. Fa: C8H6Br2N2O
InChI Key: -

Names and Identifiers of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

CAS Number

1000341-07-0

IUPAC Name

3,6-bis(bromanyl)-5-methoxy-1H-pyrrolo[3,2-b]pyridine

Canonical SMILES

COC1=C(C=C2C(=N1)C(=CN2)Br)Br

Physical and chemical properties of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

Acidity coefficient

11.77±0.40(Predicted)

Boiling Point

378.9±37.0 °C at 760 mmHg

Density

2.0±0.1 g/cm3

Exact Mass

303.884674

Flash Point

182.9±26.5 °C

Index of Refraction

1.702

LogP

2.42

Molecular Formula

C8H6Br2N2O

Molecular Weight

305.954

PSA

37.91000

Vapour Pressure

0.0±0.8 mmHg at 25°C

Applications of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

3,6-Dibromo-5-methoxy-1H-pyrrolo[3,2-b]pyridine has several applications:

  • Pharmaceutical Development: Its potential as an FGFR inhibitor makes it a candidate for cancer treatment research.
  • Material Science: Due to its unique structure, it may find applications in developing new materials with specific electronic or optical properties.

Interaction Studies of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

Interaction studies have shown that 3,6-dibromo-5-methoxy-1H-pyrrolo[3,2-b]pyridine interacts effectively with various biological targets. In particular, its binding affinity to FGFRs has been highlighted in studies aimed at understanding its mechanism of action in inhibiting cancer cell proliferation .

Biological Activity of 3,6-DIBROMO-5-METHOXY-4-AZAINDOLE

Research indicates that 3,6-dibromo-5-methoxy-1H-pyrrolo[3,2-b]pyridine exhibits significant biological activity. It has been studied for its potential as an inhibitor of fibroblast growth factor receptors (FGFRs), which are implicated in various cancers. The compound's ability to bind to FGFRs suggests it may play a role in cancer therapeutics by inhibiting tumor growth and proliferation .