structure of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

CAS No.: 1000341-69-4
M. Wt: 275.928
M. Fa: C7H4Br2N2
InChI Key: QVELAICZDMCCGN-UHFFFAOYSA-N
Appearance: White Solid

Names and Identifiers of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

CAS Number

1000341-69-4

MDL Number

MFCD09749985

IUPAC Name

3,6-dibromo-1H-pyrrolo[3,2-c]pyridine

InChI

InChI=1S/C7H4Br2N2/c8-5-3-10-6-1-7(9)11-2-4(5)6/h1-3,10H

InChIKey

QVELAICZDMCCGN-UHFFFAOYSA-N

Canonical SMILES

C1=C2C(=CN=C1Br)C(=CN2)Br

UNSPSC Code

12352100

Physical and chemical properties of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Boiling Point

417.3±40.0 °C at 760 mmHg

Density

2.2±0.1 g/cm3

Exact Mass

273.874115

Flash Point

206.2±27.3 °C

Index of Refraction

1.751

LogP

2.23

Molecular Formula

C7H4Br2N2

Molecular Weight

275.928

PSA

28.68000

Storage condition

under inert gas (nitrogen or Argon) at 2-8°C

Vapour Pressure

0.0±0.9 mmHg at 25°C

Safety Information of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Due to its unique chemical structure and biological activity, 3,6-dibromo-1H-pyrrolo[3,2-c]pyridine finds applications in:

  • Pharmaceutical Development: As a scaffold for developing new drugs targeting various diseases.
  • Chemical Research: In synthetic chemistry as an intermediate for creating more complex molecules.
  • Biological Studies: Investigating its role as an inhibitor in cellular pathways related to cancer and other conditions.

Interaction Studies of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Studies involving 3,6-dibromo-1H-pyrrolo[3,2-c]pyridine have focused on its interactions with specific proteins involved in disease mechanisms. For instance, it has shown potential as an FGFR inhibitor, which is crucial in various signaling pathways associated with cell growth and differentiation. The compound's binding affinity and interaction dynamics with target proteins are subjects of ongoing research, aiming to elucidate its mechanisms of action in biological systems.

Biological Activity of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Research indicates that 3,6-dibromo-1H-pyrrolo[3,2-c]pyridine exhibits significant biological activity. It has been studied for its potential as an inhibitor of various biological targets, including fibroblast growth factor receptors (FGFR) and other kinases. This compound's unique structure allows it to interact effectively with protein binding sites, potentially leading to therapeutic applications in cancer treatment and other diseases.

Physical sample testing spectrum (NMR) of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine

Physical sample testing spectrum (NMR) of 3,6-Dibromo-1H-pyrrolo[3,2-c]pyridine