3-Amino-4-bromobenzenesulfonamide
Names and Identifiers of 3-Amino-4-bromobenzenesulfonamide
CAS Number |
100367-90-6 |
|---|---|
MDL Number |
MFCD09949821 |
IUPAC Name |
3-amino-4-bromobenzenesulfonamide |
InChI |
InChI=1S/C6H7BrN2O2S/c7-5-2-1-4(3-6(5)8)12(9,10)11/h1-3H,8H2,(H2,9,10,11) |
InChIKey |
AUFMHQSAEAOXHZ-UHFFFAOYSA-N |
Canonical SMILES |
C1=CC(=C(C=C1S(=O)(=O)N)N)Br |
UNSPSC Code |
12352100 |
Physical and chemical properties of 3-Amino-4-bromobenzenesulfonamide
Boiling Point |
435.1±55.0 °C(Predicted) |
|---|---|
Density |
1.834±0.06 g/cm3(Predicted) |
H Bond Acceptors |
3 |
H Bond Donors |
2 |
LogP |
0.519103257 |
Molecular Formula |
C6H7BrN2O2S |
Molecular Weight |
251.10 |
Safety Information of 3-Amino-4-bromobenzenesulfonamide
Applications of 3-Amino-4-bromobenzenesulfonamide
3-Amino-4-bromobenzene-1-sulfonamide finds applications in various fields:
- Pharmaceuticals: It serves as a key intermediate in the synthesis of sulfonamide-based drugs and other biologically active compounds.
- Chemical Synthesis: The compound is utilized in the production of dyes and complex organic molecules.
- Material Science: It contributes to the development of functional materials with specific properties.
Interaction Studies of 3-Amino-4-bromobenzenesulfonamide
Research into the interactions of 3-amino-4-bromobenzene-1-sulfonamide with biological molecules has shown that it can modulate enzyme activity and influence cellular processes. Its ability to bind to specific enzymes suggests potential applications in drug design aimed at targeting bacterial infections or other diseases involving dysregulated enzyme activity.
Biological Activity of 3-Amino-4-bromobenzenesulfonamide
This compound exhibits significant biological activity, primarily due to its ability to inhibit bacterial growth. It acts as a competitive inhibitor of dihydropteroate synthetase, an enzyme crucial for folic acid synthesis in bacteria. By disrupting this pathway, 3-amino-4-bromobenzene-1-sulfonamide effectively inhibits bacterial reproduction and growth, making it useful in the development of antibacterial agents.
Physical sample testing spectrum (NMR) of 3-Amino-4-bromobenzenesulfonamide
