3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
CAS No.:
1000342-21-1
M. Wt:
265.030
M. Fa:
C8H4BrF3N2
InChI Key:
FNSKQNJDJIKPPC-UHFFFAOYSA-N
Appearance:
White Solid
Names and Identifiers of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
CAS Number |
1000342-21-1 |
|---|---|
MDL Number |
MFCD09749936 |
IUPAC Name |
3-bromo-4-(trifluoromethyl)-2H-indazole |
InChI |
InChI=1S/C8H4BrF3N2/c9-7-6-4(8(10,11)12)2-1-3-5(6)13-14-7/h1-3H,(H,13,14) |
InChIKey |
FNSKQNJDJIKPPC-UHFFFAOYSA-N |
Canonical SMILES |
FC(F)(F)C1=CC=CC2=C1C(Br)=NN2 |
UNSPSC Code |
12352100 |
Physical and chemical properties of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
Boiling Point |
328.1±37.0 °C at 760 mmHg |
|---|---|
Density |
1.8±0.1 g/cm3 |
Exact Mass |
263.950989 |
Flash Point |
152.3±26.5 °C |
Index of Refraction |
1.596 |
LogP |
3.46 |
Molecular Formula |
C8H4BrF3N2 |
Molecular Weight |
265.030 |
PSA |
28.68000 |
Storage condition |
2-8°C |
Vapour Pressure |
0.0±0.7 mmHg at 25°C |
Safety Information of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
Applications of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
3-Bromo-4-(trifluoromethyl)-1H-indazole has several applications in organic synthesis and medicinal chemistry:
- Catalyst in Organic Reactions: It serves as a catalyst in various organic reactions due to its unique structure.
- Precursor for Drug Development: This compound can be utilized as a precursor for synthesizing other biologically active compounds.
- Research Tool: It is often used in research settings to study the properties and reactivity of indazole derivatives.
Interaction Studies of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
Studies on 3-Bromo-4-(trifluoromethyl)-1H-indazole have explored its interactions with various biological targets. These studies aim to elucidate its mechanism of action and potential therapeutic effects:
- Receptor Binding Studies: Investigations into how this compound interacts with specific receptors may provide insights into its biological activity.
- Enzyme Inhibition Studies: Understanding how it inhibits or activates certain enzymes could reveal its potential uses in treating diseases.
Biological Activity of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
Indazole derivatives, including 3-Bromo-4-(trifluoromethyl)-1H-indazole, exhibit various biological activities. Research has indicated that these compounds may possess:
- Antimicrobial Properties: Some studies suggest that indazole derivatives have potential as antimicrobial agents.
- Anti-inflammatory Effects: Certain derivatives show promise in reducing inflammation.
- Anticancer Activity: There is ongoing research into the anticancer properties of indazoles, with some showing effectiveness against specific cancer cell lines.
Physical sample testing spectrum (NMR) of 3-BROMO-4-TRIFLUOROMETHYL (1H)INDAZOLE
