structure of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

CAS No.: 1004-65-5
M. Wt: 133.151
M. Fa: C7H7N3
InChI Key: XKXVBWLYSGMTCK-UHFFFAOYSA-N
Appearance: Pale-yellow Solid

Names and Identifiers of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

CAS Number

1004-65-5

MDL Number

MFCD00498952

IUPAC Name

3-methyl-[1,2,4]triazolo[4,3-a]pyridine

InChI

InChI=1S/C7H7N3/c1-6-8-9-7-4-2-3-5-10(6)7/h2-5H,1H3

InChIKey

XKXVBWLYSGMTCK-UHFFFAOYSA-N

Canonical SMILES

CC1=NN=C2N1C=CC=C2

UNII

6H8Y5P98VZ

UNSPSC Code

12352100

Physical and chemical properties of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Acidity coefficient

3.97±0.50(Predicted)

Density

1.2±0.1 g/cm3

Exact Mass

133.063995

Index of Refraction

1.659

LogP

0.94

Melting Point

134℃

Molecular Formula

C7H7N3

Molecular Weight

133.151

PSA

30.19000

Storage condition

Inert atmosphere,Room Temperature

Safety Information of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Pictograms

Signal Word

Warning

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

The unique properties of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine make it valuable in several areas:

  • Pharmaceuticals: Its derivatives are being explored for use as potential therapeutic agents against various diseases due to their biological activities.
  • Material Science: The compound's optical properties allow it to be utilized in developing organic light-emitting diodes and other electronic materials.
  • Chemosensors: The ability of triazolopyridines to coordinate with metal ions makes them suitable for use in chemosensors for detecting environmental pollutants.

Interaction Studies of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Studies involving 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine have focused on its interactions with biological targets:

  • Receptor Binding Studies: Research has shown that certain derivatives can bind effectively to glutamate receptors and other neurotransmitter systems.
  • Metal Ion Coordination: The nitrogen atoms in the triazole and pyridine rings can coordinate with transition metals, forming complexes that may exhibit enhanced catalytic properties or fluorescence characteristics.

Biological Activity of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Research has demonstrated that derivatives of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine exhibit significant biological activities. These include:

  • Antimicrobial Properties: Some derivatives have shown effectiveness against bacterial and fungal strains.
  • Anticancer Activity: Certain compounds within this class have been evaluated for their potential to inhibit tumor growth in various cancer cell lines.
  • Neurological Effects: Studies indicate that these compounds may interact with glutamate receptors and could be explored as treatments for psychiatric disorders such as schizophrenia.

Physical sample testing spectrum (NMR) of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Physical sample testing spectrum (NMR) of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

Retrosynthesis analysis of 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine

  • Route#1

    Cas:108-24-7
    Cas:4930-98-7
    Cas:1004-65-5
  • Route#2

    Cas:7707-99-5
    Cas:1004-65-5