4'-anilinotoluene-4-sulphonanilide

Benzenesulfonamide, 4-methyl-N-[4-(phenylamino)phenyl]- has various applications in research and industry:

• Analytical Chemistry: It can be analyzed using high-performance liquid chromatography (HPLC), which is useful for separating and purifying compounds in pharmacokinetic studies.
• Pharmaceutical Development: Due to its biological activity, it serves as a lead compound for developing new therapeutic agents targeting carbonic anhydrase or other biological pathways.
• Material Science: The compound may also find applications in materials science due to its unique structural properties.

Studies on interaction profiles indicate that benzenesulfonamide derivatives can interact with various biological targets, including enzymes involved in metabolic pathways. Specific interactions with carbonic anhydrase isoforms have been documented, highlighting their potential as enzyme inhibitors. Further research into these interactions could elucidate mechanisms of action and inform drug design strategies.

Benzenesulfonamide derivatives have been studied for their biological activities, particularly as inhibitors of carbonic anhydrase enzymes, which play crucial roles in physiological processes such as respiration and acid-base balance. Research indicates that certain benzenesulfonamides exhibit significant inhibitory effects against specific cancer cell lines, suggesting potential applications in cancer therapy. The compound has been evaluated by the National Cancer Institute for its anticancer properties, indicating its relevance in medicinal chemistry.