structure of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

CAS No.: 1000342-57-3
M. Wt: 256.487
M. Fa: C8H3BrClN3
InChI Key: -

Names and Identifiers of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

CAS Number

1000342-57-3

IUPAC Name

4-bromanyl-3-chloranyl-2H-indazole-6-carbonitrile

Canonical SMILES

C1=C(C=C(C2=C(NN=C21)Cl)Br)C#N

Physical and chemical properties of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

Boiling Point

428.6±40.0 °C at 760 mmHg

Density

2.0±0.1 g/cm3

Exact Mass

254.919876

Flash Point

213.0±27.3 °C

Index of Refraction

1.746

LogP

2.63

Molecular Formula

C8H3BrClN3

Molecular Weight

256.487

PSA

52.47000

Vapour Pressure

0.0±1.0 mmHg at 25°C

Applications of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

The applications of 4-Bromo-3-chloro-1H-indazole-6-carbonitrile span several fields:

  • Medicinal Chemistry: Its unique structure makes it a candidate for developing new pharmaceuticals targeting various diseases.
  • Material Science: The compound may also find uses in the development of advanced materials due to its electronic properties.
  • Research: It serves as an important intermediate in organic synthesis and drug discovery.

Interaction Studies of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

Studies on the interactions of 4-Bromo-3-chloro-1H-indazole-6-carbonitrile with biological systems are crucial for understanding its potential therapeutic effects. It has been noted to act as an inhibitor for certain cytochrome P450 enzymes, which are essential for drug metabolism. This property may influence its pharmacokinetics and therapeutic efficacy.

Biological Activity of 4-BROMO-3-CHLORO-6-CYANO (1H)INDAZOLE

Indazole derivatives, including 4-Bromo-3-chloro-1H-indazole-6-carbonitrile, have shown significant biological activities. Research indicates potential anti-cancer properties, antimicrobial effects, and possible applications in treating neurological disorders. The presence of halogen substituents may enhance these biological activities by affecting the compound's interaction with biological targets.