structure of 4-FLUORO-3-CHLORO (1H)INDAZOLE

4-FLUORO-3-CHLORO (1H)INDAZOLE

CAS No.: 1000340-79-3
M. Wt: 170.572
M. Fa: C7H4ClFN2
InChI Key: -

Names and Identifiers of 4-FLUORO-3-CHLORO (1H)INDAZOLE

CAS Number

1000340-79-3

IUPAC Name

3-chloranyl-4-fluoranyl-2H-indazole

Canonical SMILES

C1=CC2=NNC(=C2C(=C1)F)Cl

Physical and chemical properties of 4-FLUORO-3-CHLORO (1H)INDAZOLE

Boiling Point

136.7±33.0 °C at 760 mmHg

Density

1.5±0.1 g/cm3

Exact Mass

170.004700

Flash Point

36.5±25.4 °C

Index of Refraction

1.669

LogP

2.34

Molecular Formula

C7H4ClFN2

Molecular Weight

170.572

PSA

28.68000

Vapour Pressure

7.3±0.3 mmHg at 25°C

Applications of 4-FLUORO-3-CHLORO (1H)INDAZOLE

3-Chloro-4-fluoro-1H-indazole has several applications across multiple fields:

  • Medicinal Chemistry: It is investigated for its potential use in drug development, particularly as inhibitors of specific enzymes or receptors.
  • Biological Research: The compound is studied for its diverse biological activities, including antimicrobial and anticancer properties.
  • Material Science: It may be utilized in developing new materials with specific properties, such as fluorescence or conductivity.

Interaction Studies of 4-FLUORO-3-CHLORO (1H)INDAZOLE

The interaction studies of 3-Chloro-4-fluoro-1H-indazole focus on its binding affinity to various molecular targets. Research shows that the unique combination of halogen substituents enhances its reactivity and potential biological activity. Mechanistic studies reveal that the compound can form reactive intermediates that interact with cellular components, leading to inhibition or activation of specific pathways.

Biological Activity of 4-FLUORO-3-CHLORO (1H)INDAZOLE

Research indicates that 3-Chloro-4-fluoro-1H-indazole exhibits notable biological activities. It has been studied for its potential antimicrobial and anticancer properties. The presence of halogen substituents enhances its binding affinity to specific molecular targets, which may influence various biological pathways. This compound's mechanism of action often involves interaction with enzymes or receptors, potentially modulating their activity.