structure of 4-Fluoro-7-methoxy-1H-indole

4-Fluoro-7-methoxy-1H-indole

CAS No.: 1000341-63-8
M. Wt: 165.164
M. Fa: C9H8FNO
InChI Key: MCUHJHBCMVCIMA-UHFFFAOYSA-N

Names and Identifiers of 4-Fluoro-7-methoxy-1H-indole

CAS Number

1000341-63-8

MDL Number

MFCD09749910

IUPAC Name

4-fluoro-7-methoxy-1H-indole

InChI

InChI=1S/C9H8FNO/c1-12-8-3-2-7(10)6-4-5-11-9(6)8/h2-5,11H,1H3

InChIKey

MCUHJHBCMVCIMA-UHFFFAOYSA-N

Canonical SMILES

COC1=C2C(=C(C=C1)F)C=CN2

UNSPSC Code

12352100

Physical and chemical properties of 4-Fluoro-7-methoxy-1H-indole

Acidity coefficient

15.89±0.30(Predicted)

Boiling Point

314.9±22.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

165.058990

Flash Point

144.3±22.3 °C

H Bond Acceptors

1

H Bond Donors

1

Index of Refraction

1.612

LogP

2.18

Molecular Formula

C9H8FNO

Molecular Weight

165.164

PSA

25.02000

Storage condition

2-8°C

Vapour Pressure

0.0±0.6 mmHg at 25°C

Safety Information of 4-Fluoro-7-methoxy-1H-indole

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 4-Fluoro-7-methoxy-1H-indole

4-Fluoro-7-methoxy-1H-indole has potential applications in various fields:

  • Pharmaceutical Development: It serves as a scaffold for designing new drugs targeting various diseases due to its biological activities.
  • Material Science: Its unique properties may allow it to be used in developing organic electronic materials or sensors.
  • Chemical Research: It is valuable in synthetic organic chemistry for exploring new reaction pathways or mechanisms involving indole derivatives.

Interaction Studies of 4-Fluoro-7-methoxy-1H-indole

Studies on 4-Fluoro-7-methoxy-1H-indole's interactions with biological targets reveal its potential efficacy:

  • Protein Binding Studies: Investigations into how this compound interacts with specific proteins can provide insights into its mechanism of action and therapeutic potential.
  • Receptor Binding Affinity: The compound's ability to bind to various receptors (e.g., serotonin receptors) is crucial for understanding its pharmacological effects.

Biological Activity of 4-Fluoro-7-methoxy-1H-indole

Indole derivatives, including 4-Fluoro-7-methoxy-1H-indole, are known for their diverse biological activities. They have been studied for their potential as:

  • Antimicrobial Agents: Some studies indicate that compounds with similar structures exhibit significant antimicrobial properties.
  • Anticancer Activity: Indoles are often investigated for their ability to inhibit cancer cell growth through various mechanisms, including apoptosis induction and cell cycle arrest.
  • Neuroprotective Effects: Certain indole derivatives have shown promise in protecting neuronal cells from oxidative stress and neurodegenerative diseases.