structure of 4-chloro-7-fluoro-1H-indole

4-chloro-7-fluoro-1H-indole

CAS No.: 1000341-78-5
M. Wt: 169.583
M. Fa: C8H5ClFN
InChI Key: KWILNHHBZCXENW-UHFFFAOYSA-N

Names and Identifiers of 4-chloro-7-fluoro-1H-indole

CAS Number

1000341-78-5

EC Number

867-141-5

MDL Number

MFCD03095315

IUPAC Name

4-chloro-7-fluoro-1H-indole

InChI

InChI=1S/C8H5ClFN/c9-6-1-2-7(10)8-5(6)3-4-11-8/h1-4,11H

InChIKey

KWILNHHBZCXENW-UHFFFAOYSA-N

Canonical SMILES

C1=CC(=C2C=CNC2=C1F)Cl

UNSPSC Code

12352100

Physical and chemical properties of 4-chloro-7-fluoro-1H-indole

Boiling Point

295.4±20.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

169.009460

Flash Point

132.5±21.8 °C

H Bond Acceptors

0

H Bond Donors

1

Index of Refraction

1.657

LogP

2.74

Molecular Formula

C8H5ClFN

Molecular Weight

169.583

PSA

15.79000

Vapour Pressure

0.0±0.6 mmHg at 25°C

Safety Information of 4-chloro-7-fluoro-1H-indole

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 4-chloro-7-fluoro-1H-indole

4-Chloro-7-fluoro-1H-indole has several applications, particularly in:

  • Medicinal Chemistry: As a lead compound for developing new therapeutic agents targeting various diseases.
  • Biochemical Research: Utilized in studies involving enzyme inhibition and protein interaction assays.
  • Material Science: Potential use in organic electronics and photonic devices due to its unique electronic properties.

Interaction Studies of 4-chloro-7-fluoro-1H-indole

Studies on the interactions of 4-chloro-7-fluoro-1H-indole with biological macromolecules reveal its potential as a modulator of enzyme activity and cellular signaling pathways. The compound can induce conformational changes in target proteins, altering their function and potentially leading to therapeutic outcomes.

Biological Activity of 4-chloro-7-fluoro-1H-indole

Indole derivatives, including 4-chloro-7-fluoro-1H-indole, exhibit a wide range of biological activities. These include:

  • Antiviral: Potential effectiveness against various viral infections.
  • Anti-inflammatory: Ability to reduce inflammation in biological tissues.
  • Anticancer: Inhibition of cancer cell proliferation through various mechanisms.
  • Antimicrobial: Activity against bacteria and fungi.

The compound's interactions with enzymes and proteins can lead to significant changes in cellular processes, influencing pathways related to cell proliferation, differentiation, and apoptosis.