4-fluoro-5-nitro-1H-indole
CAS No.:
1003858-69-2
M. Wt:
180.13600
M. Fa:
C8H5FN2O2
InChI Key:
UTYWHDIQWCMUNW-UHFFFAOYSA-N
Appearance:
Yellow Solid
Names and Identifiers of 4-fluoro-5-nitro-1H-indole
CAS Number |
1003858-69-2 |
|---|---|
MDL Number |
MFCD26408173 |
IUPAC Name |
4-fluoro-5-nitro-1H-indole |
InChI |
InChI=1S/C8H5FN2O2/c9-8-5-3-4-10-6(5)1-2-7(8)11(12)13/h1-4,10H |
InChIKey |
UTYWHDIQWCMUNW-UHFFFAOYSA-N |
Canonical SMILES |
C1=CC(=C(C2=C1NC=C2)F)[N+](=O)[O-] |
UNSPSC Code |
12352100 |
Physical and chemical properties of 4-fluoro-5-nitro-1H-indole
Exact Mass |
180.03400 |
|---|---|
H Bond Acceptors |
2 |
H Bond Donors |
1 |
LogP |
2.73840 |
Molecular Formula |
C8H5FN2O2 |
Molecular Weight |
180.13600 |
PSA |
61.61000 |
Storage condition |
2-8℃ |
Safety Information of 4-fluoro-5-nitro-1H-indole
Applications of 4-fluoro-5-nitro-1H-indole
The applications of 4-fluoro-5-nitro-1H-indole are diverse:
- Pharmaceuticals: Due to its biological activity, it serves as a scaffold for designing new drugs targeting various diseases.
- Research: It is used in studies aimed at understanding the mechanisms of action of indole-based compounds and their derivatives.
Interaction Studies of 4-fluoro-5-nitro-1H-indole
Interaction studies have shown that 4-fluoro-5-nitro-1H-indole can interact with various biological targets:
- Protein Binding: Investigations into how this compound binds to proteins can reveal insights into its mechanism of action and potential therapeutic effects.
- Receptor Activity: Studies on its interaction with specific receptors may help elucidate its role in modulating biological pathways.
Biological Activity of 4-fluoro-5-nitro-1H-indole
4-Fluoro-5-nitro-1H-indole exhibits notable biological activities:
- Antimicrobial Properties: Research indicates that derivatives of this compound possess antimicrobial activities, making them potential candidates for developing new antibiotics.
- Anticancer Potential: Some studies have suggested that indole derivatives can inhibit cancer cell proliferation, pointing to their potential in cancer therapy.
Physical sample testing spectrum (NMR) of 4-fluoro-5-nitro-1H-indole
