4-fluoro-5-nitro-2,3-dihydro-1H-indole
CAS No.:
1003858-68-1
M. Wt:
182.15
M. Fa:
C8H7FN2O2
InChI Key:
IZJPDEDMUHMSKG-UHFFFAOYSA-N
Appearance:
Orange Solid
Names and Identifiers of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
CAS Number |
1003858-68-1 |
|---|---|
EC Number |
835-277-4 |
IUPAC Name |
4-fluoro-5-nitro-2,3-dihydro-1H-indole |
InChI |
InChI=1S/C8H7FN2O2/c9-8-5-3-4-10-6(5)1-2-7(8)11(12)13/h1-2,10H,3-4H2 |
InChIKey |
IZJPDEDMUHMSKG-UHFFFAOYSA-N |
Canonical SMILES |
C1CNC2=C1C(=C(C=C2)[N+](=O)[O-])F |
Physical and chemical properties of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
Acidity coefficient |
-0.05±0.20(Predicted) |
|---|---|
Boiling Point |
323.2±42.0 °C(Predicted) |
Density |
1.394±0.06 g/cm3(Predicted) |
Molecular Formula |
C8H7FN2O2 |
Molecular Weight |
182.15 |
Safety Information of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
Applications of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
4-Fluoro-5-nitro-2,3-dihydro-1H-indole has potential applications in:
- Pharmaceutical Development: Its unique structure may lead to new drugs targeting various diseases, particularly those involving neurotransmitter systems.
- Material Science: As an organic compound with distinct electronic properties, it may find applications in organic electronics or photonic devices.
Interaction Studies of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
Research on the interaction of 4-fluoro-5-nitro-2,3-dihydro-1H-indole with biological targets is limited but suggests potential interactions with:
- Serotonin Transporters: Similar compounds have shown affinity for serotonin transporters, indicating possible antidepressant effects.
- Dopamine Receptors: Some studies suggest that related indole derivatives may modulate dopamine receptor activity, which could be beneficial in treating neurological disorders.
Biological Activity of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
Indole derivatives, including 4-fluoro-5-nitro-2,3-dihydro-1H-indole, have been studied for various biological activities. These compounds are known for their potential as:
- Antimicrobial Agents: Indoles exhibit activity against various bacterial strains.
- Anticancer Agents: Certain indole derivatives have shown promise in inhibiting cancer cell proliferation.
- Neuroprotective Effects: Indoles are being researched for their potential in treating neurodegenerative diseases due to their ability to modulate neurotransmitter systems.
Physical sample testing spectrum (NMR) of 4-fluoro-5-nitro-2,3-dihydro-1H-indole
