structure of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

CAS No.: 1000342-50-6
M. Wt: 293.492
M. Fa: C7H5ClIN3
InChI Key: -

Names and Identifiers of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

CAS Number

1000342-50-6

IUPAC Name

6-chloranyl-3-iodanyl-2H-indazol-5-amine

Canonical SMILES

C1=C(C(=CC2=NNC(=C21)I)Cl)N

Physical and chemical properties of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

Boiling Point

456.5±40.0 °C at 760 mmHg

Density

2.2±0.1 g/cm3

Exact Mass

292.921661

Flash Point

229.9±27.3 °C

Index of Refraction

1.849

LogP

2.95

Molecular Formula

C7H5ClIN3

Molecular Weight

293.492

PSA

54.70000

Vapour Pressure

0.0±1.1 mmHg at 25°C

Applications of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

The primary applications of 6-Chloro-3-iodo-1H-indazol-5-amine include:

  • Pharmaceutical Development: Its structure makes it a valuable candidate for developing new anti-cancer drugs.
  • Biochemical Research: It serves as a tool compound for studying kinase inhibition and other biological pathways.
  • Material Science: Potential applications in organic electronics and photonic devices due to its electronic properties.

Interaction Studies of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

Interaction studies have shown that 6-Chloro-3-iodo-1H-indazol-5-amine interacts with various biological targets, particularly kinases involved in tumor growth and proliferation. These interactions are essential for understanding its mechanism of action and optimizing its efficacy as a therapeutic agent.

Biological Activity of 5-AMINO-6-CHLORO-3-IODO (1H)INDAZOLE

6-Chloro-3-iodo-1H-indazol-5-amine exhibits significant biological activity, particularly in the realm of cancer research. It has been identified as a potential inhibitor of certain kinases involved in cancer progression. Studies have shown that indazole derivatives can exhibit anti-cancer properties, making this compound a candidate for further investigation in therapeutic applications.