structure of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

CAS No.: 1000342-51-7
M. Wt: 336.955
M. Fa: C8H6BrIN2
InChI Key: -

Names and Identifiers of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

CAS Number

1000342-51-7

IUPAC Name

6-bromanyl-3-iodanyl-5-methyl-2H-indazole

Canonical SMILES

CC1=CC2=C(NN=C2C=C1Br)I

Physical and chemical properties of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

Boiling Point

421.3±40.0 °C at 760 mmHg

Density

2.3±0.1 g/cm3

Exact Mass

335.875885

Flash Point

208.6±27.3 °C

Index of Refraction

1.768

LogP

4.38

Molecular Formula

C8H6BrIN2

Molecular Weight

336.955

PSA

28.68000

Storage condition

2-8°C

Vapour Pressure

0.0±1.0 mmHg at 25°C

Applications of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

6-Bromo-3-iodo-5-methyl-1H-indazole has various applications in research and industry:

  • Medicinal Chemistry: Due to its biological activity, it is being explored for drug development targeting viral infections and neurological disorders.
  • Chemical Research: Its unique structure makes it a valuable intermediate in synthetic organic chemistry for creating more complex molecules with desired properties.

Interaction Studies of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

Research into the interactions of 6-Bromo-3-iodo-5-methyl-1H-indazole with biological systems is ongoing. Studies typically focus on:

  • Binding Affinity: Understanding how this compound interacts with specific receptors or enzymes.
  • Mechanism of Action: Investigating how it exerts its biological effects at the molecular level.

Such studies are crucial for determining its potential therapeutic uses and safety profile.

Biological Activity of 6-BROMO-3-IODO-5-METHYL (1H)INDAZOLE

Compounds in the indazole class, including 6-Bromo-3-iodo-5-methyl-1H-indazole, have been investigated for their biological activities. They have shown promise in various therapeutic areas, including:

  • Antiviral Activity: Indazole derivatives have been explored as potential inhibitors of HIV protease, an enzyme crucial for the maturation of infectious HIV virions.
  • Neuropharmacological Effects: These compounds may act as serotonin receptor antagonists, influencing neurotransmitter action in the brain and potentially aiding in the treatment of mood disorders.
  • Metabolic Regulation: Some indazoles are being studied for their role as aldol reductase inhibitors, which could be significant in managing diabetes-related complications.