structure of 6-Methoxy-1H-indazol-4-amine

6-Methoxy-1H-indazol-4-amine

CAS No.: 1000341-20-7
M. Wt: 163.177
M. Fa: C8H9N3O
InChI Key: GFDOZLUNMUNFEY-UHFFFAOYSA-N

Names and Identifiers of 6-Methoxy-1H-indazol-4-amine

CAS Number

1000341-20-7

MDL Number

MFCD09880192

IUPAC Name

6-methoxy-1H-indazol-4-amine

InChI

InChI=1S/C8H9N3O/c1-12-5-2-7(9)6-4-10-11-8(6)3-5/h2-4H,9H2,1H3,(H,10,11)

InChIKey

GFDOZLUNMUNFEY-UHFFFAOYSA-N

Canonical SMILES

COC1=CC(=C2C=NNC2=C1)N

UNSPSC Code

12352100

Physical and chemical properties of 6-Methoxy-1H-indazol-4-amine

Boiling Point

413.5±25.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

163.074554

Flash Point

203.9±23.2 °C

H Bond Acceptors

3

H Bond Donors

2

Index of Refraction

1.712

LogP

0.44

Molecular Formula

C8H9N3O

Molecular Weight

163.177

PSA

63.93000

Vapour Pressure

0.0±1.0 mmHg at 25°C

Safety Information of 6-Methoxy-1H-indazol-4-amine

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of 6-Methoxy-1H-indazol-4-amine

The applications of 6-methoxy-1H-indazol-4-amine span various fields:

  • Pharmaceutical Development: Its potential as a therapeutic agent for neurological disorders makes it a candidate for drug development.
  • Chemical Research: It serves as a building block in synthetic organic chemistry due to its versatile reactivity.
  • Agricultural Chemistry: Some derivatives have been explored for herbicidal properties, highlighting its utility in agrochemicals.

Interaction Studies of 6-Methoxy-1H-indazol-4-amine

Interaction studies have focused on understanding how 6-methoxy-1H-indazol-4-amine interacts with biological targets:

  • Enzyme Inhibition Profiles: Studies have quantified its inhibitory effects on monoamine oxidase enzymes, revealing structure-activity relationships that guide further modifications for enhanced potency.
  • Binding Affinities: Investigations into its binding affinities with neurotransmitter receptors are ongoing to assess its potential therapeutic effects.

Biological Activity of 6-Methoxy-1H-indazol-4-amine

Research indicates that 6-methoxy-1H-indazol-4-amine exhibits notable biological activities:

  • Monoamine Oxidase Inhibition: It has been studied as an inhibitor of monoamine oxidase enzymes, which play a critical role in neurotransmitter metabolism. This inhibition has implications for treating mood disorders.
  • Antimicrobial Properties: Preliminary studies suggest potential antimicrobial effects against various pathogens, although further research is needed to quantify this activity.