7-Fluoro-2-methoxy-1,5-naphthyridine
Names and Identifiers of 7-Fluoro-2-methoxy-1,5-naphthyridine
CAS Number |
1003944-32-8 |
|---|---|
MDL Number |
MFCD16875497 |
IUPAC Name |
7-fluoro-2-methoxy-1,5-naphthyridine |
InChI |
InChI=1S/C9H7FN2O/c1-13-9-3-2-7-8(12-9)4-6(10)5-11-7/h2-5H,1H3 |
InChIKey |
JRNKDUBTSNDYCD-UHFFFAOYSA-N |
Canonical SMILES |
COC1=NC2=C(C=C1)N=CC(=C2)F |
UNSPSC Code |
12352100 |
Physical and chemical properties of 7-Fluoro-2-methoxy-1,5-naphthyridine
Exact Mass |
178.05400 |
|---|---|
H Bond Acceptors |
3 |
H Bond Donors |
0 |
LogP |
1.77750 |
Melting Point |
78-79℃ |
Molecular Formula |
C9H7FN2O |
Molecular Weight |
178.16300 |
PSA |
35.01000 |
Storage condition |
Sealed in dry,Room Temperature |
Safety Information of 7-Fluoro-2-methoxy-1,5-naphthyridine
Applications of 7-Fluoro-2-methoxy-1,5-naphthyridine
7-Fluoro-2-methoxy-1,5-naphthyridine finds applications in:
- Medicinal Chemistry: Due to its biological activity, it is being explored as a lead compound for developing new drugs targeting cancer and other diseases.
- Synthetic Organic Chemistry: It serves as an intermediate in synthesizing more complex organic molecules.
- Material Science: Its unique properties may also find applications in developing new materials with specific electronic or optical characteristics.
Interaction Studies of 7-Fluoro-2-methoxy-1,5-naphthyridine
Interaction studies involving 7-fluoro-2-methoxy-1,5-naphthyridine have focused on its binding affinity to various biological targets. These studies often utilize techniques such as molecular docking and biochemical assays to evaluate how this compound interacts with enzymes or receptors implicated in disease pathways. Such interactions are crucial for understanding its potential therapeutic effects and optimizing its structure for improved efficacy.
Biological Activity of 7-Fluoro-2-methoxy-1,5-naphthyridine
Research indicates that 7-fluoro-2-methoxy-1,5-naphthyridine exhibits significant biological activity. It has been studied for its potential as an inhibitor of certain enzymes and receptors involved in various diseases. For instance, compounds within the naphthyridine class have shown promise as inhibitors of poly ADP ribose polymerase (PARP), which plays a crucial role in DNA repair mechanisms. This inhibition can lead to enhanced efficacy in cancer therapies by preventing cancer cells from repairing their DNA
Physical sample testing spectrum (NMR) of 7-Fluoro-2-methoxy-1,5-naphthyridine
