structure of Jineol

Jineol

CAS No.: 178762-28-2
M. Wt: 161.15700
M. Fa: C9H7NO2
InChI Key: IGDFDIZIHMFYGR-UHFFFAOYSA-N

Names and Identifiers of Jineol

CAS Number

178762-28-2

EC Number

849-461-7

IUPAC Name

quinoline-3,8-diol

InChI

InChI=1S/C9H7NO2/c11-7-4-6-2-1-3-8(12)9(6)10-5-7/h1-5,11-12H

InChIKey

IGDFDIZIHMFYGR-UHFFFAOYSA-N

Canonical SMILES

C1=CC2=CC(=CN=C2C(=C1)O)O

UNII

TG4DD1DY9O

Physical and chemical properties of Jineol

Boiling Point

397.2ºC at 760mmHg

Density

1.418g/cm3

Exact Mass

161.04800

Flash Point

194ºC

Index of Refraction

1.742

LogP

1.64600

Molecular Formula

C9H7NO2

Molecular Weight

161.15700

PSA

53.35000

Vapour Pressure

7.08E-07mmHg at 25°C

Safety Information of Jineol

Pictograms

Signal Word

Warning

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of Jineol

Jineol has several applications across different fields:

  • Cosmetics: Due to its anti-melanogenic properties, jineol is explored for use in skin whitening products.
  • Pharmaceuticals: Its antibacterial and anticancer activities make it a candidate for developing new therapeutic agents.
  • Food Industry: As a natural antioxidant, jineol may be used to enhance the shelf life of food products.

Interaction Studies of Jineol

Research on jineol's interactions reveals its potential to modulate various signaling pathways. For instance, it affects the extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase pathways, which are crucial in regulating melanin synthesis. These interactions suggest that jineol could be a valuable compound for further studies aimed at understanding its mechanisms of action in biological systems.

Biological Activity of Jineol

The biological activities of jineol are extensive:

  • Antioxidant Activity: Jineol exhibits potent antioxidant properties, scavenging free radicals and reducing oxidative stress through mechanisms involving hydrogen atom transfer and electron donation.
  • Antibacterial Effects: Studies show that jineol can significantly reduce bacterial cell viability and promote potassium ion release from bacterial cells, indicating its potential as an antibacterial agent.
  • Anti-cancer Properties: Jineol has been investigated for its anticancer effects, particularly in inhibiting cell proliferation and inducing apoptosis in cancer cell lines.

Retrosynthesis analysis of Jineol

  • Route#1

    Cas:214349-09-4
    Cas:178762-28-2
  • Route#2

    Cas:148-24-3
    Cas:178762-28-2
  • Route#3

    Cas:214349-04-9
    Cas:178762-28-2