L-Mannose
CAS No.:
10030-80-5
M. Wt:
180.156
M. Fa:
C6H12O6
InChI Key:
GZCGUPFRVQAUEE-BXKVDMCESA-N
Appearance:
Off white solid
Names and Identifiers of L-Mannose
CAS Number |
10030-80-5 |
|---|---|
EC Number |
233-080-2 |
MDL Number |
MFCD00136021 |
IUPAC Name |
(2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal |
InChI |
InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4-,5-,6-/m0/s1 |
InChIKey |
GZCGUPFRVQAUEE-BXKVDMCESA-N |
Canonical SMILES |
C(C(C(C(C(C=O)O)O)O)O)O |
Isomeric SMILES |
C([C@@H]([C@@H]([C@H]([C@H](C=O)O)O)O)O)O |
UNII |
2W3YE50TX8 |
Physical and chemical properties of L-Mannose
Acidity coefficient |
12.45±0.20(Predicted) |
|---|---|
Boiling Point |
527.1±50.0 °C at 760 mmHg |
BRN |
1724628 |
Density |
1.6±0.1 g/cm3 |
Exact Mass |
180.063385 |
Flash Point |
286.7±26.6 °C |
H Bond Acceptors |
6 |
H Bond Donors |
5 |
Index of Refraction |
1.573 |
LogP |
-3.17 |
Melting Point |
129-131ºC(lit.) |
Molecular Formula |
C6H12O6 |
Molecular Weight |
180.156 |
PSA |
110.38000 |
Solubility |
H2O: 0.1 g/mL, clear, colorless |
Storage condition |
Refrigerator |
Vapour Pressure |
0.0±3.1 mmHg at 25°C |
Water Solubility |
H2O: 0.1 g/mL, clear, colorless |
Safety Information of L-Mannose
Interaction Studies of L-Mannose
Research indicates that L-mannose interacts with various biological systems:
- Glycan Recognition: Its unique structure allows it to be recognized by specific lectins and receptors involved in cell signaling and pathogen recognition.
- Impact on Glycosylation Patterns: Alterations in L-mannose levels can affect glycosylation patterns of proteins, influencing their stability and activity within biological systems.
Biological Activity of L-Mannose
L-Mannose exhibits various biological activities:
- Immune Modulation: It can influence immune responses by affecting the recognition of pathogens by immune cells due to its presence on glycoproteins.
- Therapeutic Potential: L-Mannose has been studied for its potential benefits in treating urinary tract infections and other conditions linked to glycosylation defects.
- Metabolic Pathways: It plays a significant role in carbohydrate metabolism and is involved in the synthesis of important biomolecules like glycoproteins and glycolipids.
Physical sample testing spectrum (NMR) of L-Mannose
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