Morpholine hydrochloride
Names and Identifiers of Morpholine hydrochloride
CAS Number |
10024-89-2 |
|---|---|
EC Number |
233-029-4 |
MDL Number |
MFCD00035287 |
IUPAC Name |
morpholine;hydrochloride |
InChI |
InChI=1S/C4H9NO.ClH/c1-3-6-4-2-5-1;/h5H,1-4H2;1H |
InChIKey |
JXYZHMPRERWTPM-UHFFFAOYSA-N |
Canonical SMILES |
C1COCCN1.Cl |
UNII |
28G373717I |
UNSPSC Code |
12352100 |
Physical and chemical properties of Morpholine hydrochloride
Boiling Point |
106.4ºC at 760mmHg |
|---|---|
Density |
0.83g/cm3 |
Exact Mass |
123.045090 |
Flash Point |
4.4ºC |
LogP |
0.73700 |
Melting Point |
-4.9ºC |
Molecular Formula |
C4H10ClNO |
Molecular Weight |
123.581 |
PSA |
21.26000 |
Storage condition |
Store below +30°C. |
Vapour Pressure |
10.4mmHg at 25°C |
Water Solubility |
Soluble in water |
Safety Information of Morpholine hydrochloride
Applications of Morpholine hydrochloride
Morpholine hydrochloride has diverse applications across various fields:
- Industrial Uses: It is commonly used as a pH adjuster in steam systems for fossil fuel and nuclear power plants due to its volatility and corrosion protection properties.
- Organic Synthesis: It serves as a building block in the synthesis of pharmaceuticals, including antibiotics and analgesics.
- Agriculture: Morpholine derivatives are employed as fungicides and emulsifiers in fruit coatings.
Interaction Studies of Morpholine hydrochloride
Studies have shown that morpholine hydrochloride interacts significantly with various biomolecules. Its ability to form stable complexes with enzymes allows it to modulate biochemical pathways effectively. The compound's amine and ether functional groups facilitate these interactions, influencing processes such as cellular metabolism and signaling.
Biological Activity of Morpholine hydrochloride
Morpholine hydrochloride exhibits notable biological activity. It has been identified as an inhibitor of succinate dehydrogenase, an enzyme crucial for cellular respiration. By inhibiting this enzyme, morpholine hydrochloride can affect energy production within cells. The compound also influences cellular signaling pathways and gene expression, making it relevant in cancer research where its derivatives are used to enhance targeting and internalization of cancer cells.
Physical sample testing spectrum (NMR) of Morpholine hydrochloride

Cas:1258431-66-1