![structure of N-[3-(hydroxymethyl)phenyl]benzamide](https://molwiki.oss-cn-hongkong.aliyuncs.com/structure/65/80936-65-8.svg)
N-[3-(hydroxymethyl)phenyl]benzamide
Names and Identifiers of N-[3-(hydroxymethyl)phenyl]benzamide
CAS Number |
80936-65-8 |
|---|---|
IUPAC Name |
N-[3-(hydroxymethyl)phenyl]benzamide |
InChI |
InChI=1S/C14H13NO2/c16-10-11-5-4-8-13(9-11)15-14(17)12-6-2-1-3-7-12/h1-9,16H,10H2,(H,15,17) |
InChIKey |
QSLDWTSTSNGXQT-UHFFFAOYSA-N |
Canonical SMILES |
C1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)CO |
Physical and chemical properties of N-[3-(hydroxymethyl)phenyl]benzamide
Acidity coefficient |
13.36±0.70(Predicted) |
|---|---|
Boiling Point |
322.1±25.0 °C(Predicted) |
Density |
1.247±0.06 g/cm3(Predicted) |
Safety Information of N-[3-(hydroxymethyl)phenyl]benzamide
Applications of N-[3-(hydroxymethyl)phenyl]benzamide
N-[3-(hydroxymethyl)phenyl]benzamide has potential applications in:
- Medicinal Chemistry: As a lead compound for developing new drugs targeting histone deacetylases or other biological pathways.
- Chemical Research: In studies focused on structure-activity relationships (SAR) of benzamide derivatives.
- Biochemical Studies: As a tool for investigating metabolic pathways involving hydroxymethyl compounds.
Interaction Studies of N-[3-(hydroxymethyl)phenyl]benzamide
Interaction studies involving N-[3-(hydroxymethyl)phenyl]benzamide have revealed insights into its metabolic stability and interactions with biological targets. For instance, metabolites of similar compounds have been shown to exhibit varying degrees of stability and biological activity depending on their structural modifications. Understanding these interactions is crucial for optimizing its therapeutic potential.
Biological Activity of N-[3-(hydroxymethyl)phenyl]benzamide
N-[3-(hydroxymethyl)phenyl]benzamide exhibits significant biological activity, particularly in pharmacological contexts. It has been studied for its potential as an inhibitor of histone deacetylases, which are enzymes involved in modifying chromatin structure and gene expression. Compounds with similar structures have shown promise in cancer therapy due to their ability to influence gene expression related to cell proliferation and survival.
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