structure of N-Ethylmorpholine

N-Ethylmorpholine

CAS No.: 100-74-3
M. Wt: 115.17400
M. Fa: C6H13NO
InChI Key: HVCNXQOWACZAFN-UHFFFAOYSA-N
Appearance: Colorless to Yellow Liquid

Names and Identifiers of N-Ethylmorpholine

CAS Number

100-74-3

EC Number

202-885-0

MDL Number

MFCD00006177

IUPAC Name

4-ethylmorpholine

InChI

InChI=1S/C6H13NO/c1-2-7-3-5-8-6-4-7/h2-6H2,1H3

InChIKey

HVCNXQOWACZAFN-UHFFFAOYSA-N

Canonical SMILES

CCN1CCOCC1

UNII

ECM0G991FQ

UNSPSC Code

12352100

Physical and chemical properties of N-Ethylmorpholine

Acidity coefficient

7.67(at 25℃)

Boiling Point

281 °F

BRN

102969

Density

0.90

Exact Mass

115.10000

explosive limit

1.9%(V)

Flash Point

(oc) 90 °F

Freezing Point

-63℃

Index of Refraction

INDEX OF REFRACTION: 1.4400 @ 20 °C/D; SADTLER REFERENCE NUMBER: 11309 (IR, PRISM)

LogP

0.27640

Melting Point

-81 °F

Molecular Formula

C6H13NO

Molecular Weight

115.17400

Odor

Ammonia-like odor.

pH

11.8 (100g/l, H2O, 20℃)

PSA

12.47000

Sensitivity

Air Sensitive

Solubility

Miscible

Stability

Stable. Flammable. Incompatible with strong oxidizing agents. Slightly air sensitive.

Storage condition

Store below +30°C.

Vapour density

Relative vapor density (air = 1): 4.0

Vapour Pressure

6 mmHg

Water Solubility

miscible

Safety Information of N-Ethylmorpholine

Pictograms

Signal Word

Danger

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of N-Ethylmorpholine

4-Ethylmorpholine finds applications in various fields:

  • Chemical Synthesis: It serves as a reagent in organic synthesis, particularly for coupling reactions involving carboxylic acids and lactones.
  • Pharmaceuticals: Its potential biological activity makes it a candidate for drug development.
  • Industrial Uses: It is used in the formulation of coatings, adhesives, and rubber products due to its solvent properties.

Interaction Studies of N-Ethylmorpholine

Interaction studies involving 4-Ethylmorpholine focus on its reactivity with other chemicals and potential biological interactions:

  • Reactivity with Oxidizers: The compound reacts vigorously with strong oxidizing agents, posing fire and explosion hazards.
  • Biological Interactions: Studies on its toxicity indicate that it can affect human health through dermal absorption and inhalation exposure, necessitating safety precautions during handling.

Biological Activity of N-Ethylmorpholine

Research indicates that 4-Ethylmorpholine exhibits biological activity, particularly in relation to its effects on human health. Some findings include:

  • Toxicity: It is classified as a hazardous substance that can cause skin burns and eye damage upon contact. Prolonged exposure may lead to organ damage.
  • Antimicrobial Properties: Preliminary studies suggest potential antimicrobial activity, making it a candidate for further investigation in pharmaceutical applications.

Retrosynthesis analysis of N-Ethylmorpholine

  • Route#1

    Cas:78375-48-1
    Cas:100-74-3
  • Route#2

    Cas:1696-20-4
    Cas:100-74-3
  • Route#3

    Cas:3626-56-0
    Cas:100-74-3