structure of Potassium Bis(Boc)amide

Potassium Bis(Boc)amide

CAS No.: 89004-82-0
M. Wt: 255.35300
M. Fa: C10H18KNO4
InChI Key: IFXGTCUBGXFGIC-UHFFFAOYSA-M

Names and Identifiers of Potassium Bis(Boc)amide

CAS Number

89004-82-0

IUPAC Name

potassium;bis[(2-methylpropan-2-yl)oxycarbonyl]azanide

InChI

InChI=1S/C10H19NO4.K/c1-9(2,3)14-7(12)11-8(13)15-10(4,5)6;/h1-6H3,(H,11,12,13);/q;+1/p-1

InChIKey

IFXGTCUBGXFGIC-UHFFFAOYSA-M

Canonical SMILES

CC(C)(C)OC(=O)[N-]C(=O)OC(C)(C)C.[K+]

Physical and chemical properties of Potassium Bis(Boc)amide

Exact Mass

255.08700

LogP

3.23030

Molecular Formula

C10H18KNO4

Molecular Weight

255.35300

PSA

52.60000

Safety Information of Potassium Bis(Boc)amide

Pictograms

Signal Word

Warning

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of Potassium Bis(Boc)amide

Potassium Bis(Boc)amide is widely used in organic synthesis due to its role as a protecting group for amines. Its applications include:

  • Peptide Synthesis: It is employed in solid-phase peptide synthesis where protection of amino acids is crucial.
  • Drug Development: The compound serves as an intermediate in the synthesis of pharmaceuticals, particularly those containing amino functionalities.
  • Material Science: Potassium Bis(Boc)amide can also be used in creating polymeric materials that require specific functional groups for further modification.

Interaction Studies of Potassium Bis(Boc)amide

Interaction studies involving Potassium Bis(Boc)amide primarily focus on its reactivity with various nucleophiles and electrophiles during synthetic processes. These studies help elucidate its behavior under different conditions and its compatibility with other functional groups. The ability to easily remove the Boc protecting group under mild conditions makes it a favorable choice for multi-step syntheses where selective deprotection is required.

Biological Activity of Potassium Bis(Boc)amide

While specific biological activities of Potassium Bis(Boc)amide are not extensively documented, compounds with similar structures often exhibit significant biological properties. For instance, aminomethylated compounds are frequently found in bioactive natural products and may possess pharmacological activities due to their structural motifs. The stability and ease of deprotection of Boc groups also make them suitable for use in medicinal chemistry.

Physical sample testing spectrum (NMR) of Potassium Bis(Boc)amide

Physical sample testing spectrum (NMR) of Potassium Bis(Boc)amide