Potassium Bis(Boc)amide
Names and Identifiers of Potassium Bis(Boc)amide
CAS Number |
89004-82-0 |
|---|---|
IUPAC Name |
potassium;bis[(2-methylpropan-2-yl)oxycarbonyl]azanide |
InChI |
InChI=1S/C10H19NO4.K/c1-9(2,3)14-7(12)11-8(13)15-10(4,5)6;/h1-6H3,(H,11,12,13);/q;+1/p-1 |
InChIKey |
IFXGTCUBGXFGIC-UHFFFAOYSA-M |
Canonical SMILES |
CC(C)(C)OC(=O)[N-]C(=O)OC(C)(C)C.[K+] |
Physical and chemical properties of Potassium Bis(Boc)amide
Exact Mass |
255.08700 |
|---|---|
LogP |
3.23030 |
Molecular Formula |
C10H18KNO4 |
Molecular Weight |
255.35300 |
PSA |
52.60000 |
Safety Information of Potassium Bis(Boc)amide
Applications of Potassium Bis(Boc)amide
Potassium Bis(Boc)amide is widely used in organic synthesis due to its role as a protecting group for amines. Its applications include:
- Peptide Synthesis: It is employed in solid-phase peptide synthesis where protection of amino acids is crucial.
- Drug Development: The compound serves as an intermediate in the synthesis of pharmaceuticals, particularly those containing amino functionalities.
- Material Science: Potassium Bis(Boc)amide can also be used in creating polymeric materials that require specific functional groups for further modification.
Interaction Studies of Potassium Bis(Boc)amide
Interaction studies involving Potassium Bis(Boc)amide primarily focus on its reactivity with various nucleophiles and electrophiles during synthetic processes. These studies help elucidate its behavior under different conditions and its compatibility with other functional groups. The ability to easily remove the Boc protecting group under mild conditions makes it a favorable choice for multi-step syntheses where selective deprotection is required.
Biological Activity of Potassium Bis(Boc)amide
While specific biological activities of Potassium Bis(Boc)amide are not extensively documented, compounds with similar structures often exhibit significant biological properties. For instance, aminomethylated compounds are frequently found in bioactive natural products and may possess pharmacological activities due to their structural motifs. The stability and ease of deprotection of Boc groups also make them suitable for use in medicinal chemistry.
Physical sample testing spectrum (NMR) of Potassium Bis(Boc)amide
