structure of Promoxolane

Promoxolane

CAS No.: 470-43-9
M. Wt: 188.26400
M. Fa: C10H20O3
InChI Key: HHFOOWPWAXNJNY-UHFFFAOYSA-N

Names and Identifiers of Promoxolane

CAS Number

470-43-9

IUPAC Name

[2,2-di(propan-2-yl)-1,3-dioxolan-4-yl]methanol

InChI

InChI=1S/C10H20O3/c1-7(2)10(8(3)4)12-6-9(5-11)13-10/h7-9,11H,5-6H2,1-4H3

InChIKey

HHFOOWPWAXNJNY-UHFFFAOYSA-N

Canonical SMILES

CC(C)C1(OCC(O1)CO)C(C)C

UNII

JHI9RRY52E

Physical and chemical properties of Promoxolane

Boiling Point

246.8ºC at 760mmHg

Density

0.98g/cm3

Exact Mass

188.14100

Flash Point

118.4ºC

Index of Refraction

1.443

LogP

1.40240

Molecular Formula

C10H20O3

Molecular Weight

188.26400

PSA

38.69000

Vapour Pressure

0.00437mmHg at 25°C

Safety Information of Promoxolane

Pictograms

Signal Word

Warning

Safety Data Sheet

Supports customized editing of SDS information and downloading in PDF documents.

Applications of Promoxolane

Promoxolane has several applications in medicine:

  • Anxiolytic Treatment: It is primarily used to manage anxiety disorders by providing rapid relief from anxiety symptoms.
  • Muscle Relaxation: The compound is effective in treating conditions characterized by muscle tension or spasms.
  • Research Tool: In pharmacological research, Promoxolane serves as a model compound for studying central nervous system depressants and their effects on neurotransmission.

These applications underscore Promoxolane's significance in both clinical and research settings.

Interaction Studies of Promoxolane

Interaction studies involving Promoxolane have revealed important information regarding its pharmacokinetics and potential drug-drug interactions. Key findings include:

  • Synergistic Effects: When combined with other central nervous system depressants, Promoxolane may enhance sedative effects, necessitating caution in co-administration.
  • Metabolic Pathways: Understanding how Promoxolane is metabolized can inform potential interactions with drugs that affect liver enzymes involved in its clearance.

These studies are crucial for optimizing therapeutic regimens involving Promoxolane and ensuring patient safety.

Biological Activity of Promoxolane

Promoxolane exhibits significant biological activity as a muscle relaxant and anxiolytic agent. Its mechanism involves modulation of neurotransmitter systems within the central nervous system, particularly enhancing inhibitory signals that lead to decreased muscle tension and anxiety levels. The drug's effects are primarily mediated through interactions with gamma-aminobutyric acid receptors, which play a pivotal role in regulating neuronal excitability.

In pharmacological studies, Promoxolane has demonstrated effectiveness in reducing muscle spasms and providing relief from anxiety symptoms, making it a valuable therapeutic option in clinical practice.

Retrosynthesis analysis of Promoxolane

  • Route#1

    Cas:56-81-5
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    Cas:470-43-9