structure of Swertianin

Swertianin

CAS No.: 20882-75-1
M. Wt: 274.23
M. Fa: C14H10O6
InChI Key: BDBVOZGRVBXANN-UHFFFAOYSA-N

Names and Identifiers of Swertianin

CAS Number

20882-75-1

IUPAC Name

1,2,8-trihydroxy-6-methoxyxanthen-9-one

InChI

InChI=1S/C14H10O6/c1-19-6-4-8(16)11-10(5-6)20-9-3-2-7(15)13(17)12(9)14(11)18/h2-5,15-17H,1H3

InChIKey

BDBVOZGRVBXANN-UHFFFAOYSA-N

Canonical SMILES

COC1=CC(=C2C(=C1)OC3=C(C2=O)C(=C(C=C3)O)O)O

UNII

890WXQ4KC0

Physical and chemical properties of Swertianin

Boiling Point

576.9±50.0 °C at 760 mmHg

Density

1.6±0.1 g/cm3

Exact Mass

274.047729

Flash Point

226.7±23.6 °C

Index of Refraction

1.714

LogP

1.35

Melting Point

243℃

Molecular Formula

C14H10O6

Molecular Weight

274.23

PSA

100.13000

Storage condition

2-8°C

Vapour Pressure

0.0±1.7 mmHg at 25°C

Applications of Swertianin

Swertianin has several applications across different fields:

  • Pharmaceuticals: Due to its anti-inflammatory and antioxidant properties, swertianin is being explored for potential therapeutic applications in treating chronic diseases such as arthritis and cardiovascular diseases.
  • Cosmetics: Its antioxidant properties make it a candidate for inclusion in skincare products aimed at combating oxidative stress and aging.
  • Traditional Medicine: Swertianin is used in various traditional medicinal practices for its purported health benefits, including liver protection and anti-diabetic effects.

Biological Activity of Swertianin

Swertianin has demonstrated significant biological activities:

  • Antioxidant Activity: It exhibits strong antioxidant properties, effectively scavenging free radicals and inhibiting lipid peroxidation, which is crucial for protecting cells from oxidative damage.
  • Anti-inflammatory Effects: Research indicates that swertianin can inhibit the cyclooxygenase enzymes COX-1 and COX-2, reducing inflammation and pain associated with various conditions.
  • Antimicrobial Properties: Studies suggest that swertianin has potential antimicrobial effects against various pathogens, contributing to its use in traditional medicine for treating infections.

Retrosynthesis analysis of Swertianin

  • Route#1

    Cas:1444411-81-7
    Cas:20882-75-1