structure of diIC18(7) dye

diIC18(7) dye

CAS No.: 100068-60-8
M. Wt: 1013.394
M. Fa: C63H101IN2
InChI Key: JLIOTPLALDYAEH-UHFFFAOYSA-M
Appearance: Red Solid

Names and Identifiers of diIC18(7) dye

CAS Number

100068-60-8

IUPAC Name

(2E)-2-[(2E,4E,6E)-7-(3,3-dimethyl-1-octadecylindol-1-ium-2-yl)hepta-2,4,6-trienylidene]-3,3-dimethyl-1-octadecylindole;iodide

InChI

InChI=1S/C63H101N2.HI/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38-46-54-64-58-50-44-42-48-56(58)62(3,4)60(64)52-40-36-35-37-41-53-61-63(5,6)57-49-43-45-51-59(57)65(61)55-47-39-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;/h35-37,40-45,48-53H,7-34,38-39,46-47,54-55H2,1-6H3;1H/q+1;/p-1

InChIKey

JLIOTPLALDYAEH-UHFFFAOYSA-M

Canonical SMILES

CCCCCCCCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCCCCCCCC)(C)C.[I-]

Isomeric SMILES

CCCCCCCCCCCCCCCCCCN\1C2=CC=CC=C2C(/C1=C\C=C\C=C\C=C\C3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCCCCCCCC)(C)C.[I-]

Physical and chemical properties of diIC18(7) dye

Exact Mass

1012.700928

Molecular Formula

C63H101IN2

Molecular Weight

1013.394

Solubility

Methanol (Slightly, Heated), Water (Very Slightly, Heated, Sonicated)

Stability

Light Sensitive

Storage condition

-20°C

Safety Information of diIC18(7) dye

Pictograms

Signal Word

 Warning

Safety Data Sheet
Supports customized editing of SDS information and downloading in PDF documents.

Applications of diIC18(7) dye

Cy7 DiC18 has a wide range of applications in various fields:

  • Biological Imaging: Used extensively in fluorescence microscopy and in vivo imaging due to its near-infrared properties.
  • Drug Delivery Studies: Its ability to label liposomes makes it useful for studying drug delivery mechanisms.
  • Diagnostic

Interaction Studies of diIC18(7) dye

Interaction studies involving Cy7 DiC18 focus on its behavior in biological systems:

  • Membrane Interactions: Research has demonstrated how Cy7 DiC18 integrates into lipid bilayers, impacting membrane fluidity and dynamics.
  • Binding Studies: The dye has been used to investigate binding interactions with proteins and nucleic acids, providing insights into molecular recognition processes.

These studies are critical for understanding how Cy7 DiC18 can be utilized effectively in various experimental setups.

Biological Activity of diIC18(7) dye

Cy7 DiC18 demonstrates significant biological activity, particularly in cellular imaging. Its lipophilic nature allows it to integrate into lipid membranes, making it effective for:

  • Labeling Cell Membranes: It is extensively used to stain cell membranes, allowing researchers to monitor cellular dynamics.
  • Tracking Organelles: The dye can label organelles such as mitochondria and lysosomes, facilitating studies on cellular functions and interactions.
  • Viral and Lipoprotein Labeling: Cy7 DiC18 is also employed to visualize viruses and lipoproteins, contributing to virology and lipid research.

Physical sample testing spectrum (NMR) of diIC18(7) dye

Physical sample testing spectrum (NMR) of diIC18(7) dye